نتایج جستجو برای: Systemic lupus erythema-tosus

تعداد نتایج: 199156  

Journal: :iranian journal of basic medical sciences 0
nafise tabasi immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran maryam rastin immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran mahmoud mahmoudi immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran mohsen ghoryani immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran zahra mirfeizi rheumatic disease research center, imam reza hospital, mashhad university of medical sciences, mashhad, iran shahrzad zamani taghizadeh rabe immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran

objective(s):genetic and environmental factors are involved in the pathogenesis of systemic lupus erythematosus (sle). autoreactive lymphocytes are cleared through apoptosis and any disturbance in the apoptosis or clearance of apoptotic cells may disturb tolerance and lead to autoimmunity. vitamin d has anti-proliferative effects and controls cell cycle progression. in this study we investigate...

2013
CHANDRASEKHARAN KRISHNAN

The yG-globulin eluted at acid pH from kidney cortex homogenates and isolated glomeruli of five of six patients with lupus nephritis was found to exhibit antinuclear activity, which was not dependent on presence of fresh human serum. Specificity, as demonstrated by absorption of antinuclear activity, was related to nucleoprotein in three glomerular acid eluates and to DNA in two acid eluates as...

2010
Luis E. Muñoz Benjamin Frey Uwe Appelt Christina Janko Kerstin Sarter Reinhard E. Voll Peter Kern Martin Herrmann Udo S. Gaipl

Patients with systemic lupus erythematosus (SLE) often display clearance deficiencies for various targets like apoptotic cells. Most of the in vitro phagocytosis assays have been performed with leukocyte preparations from patients with SLE and may, therefore, be influenced by immunosuppressive drugs. We isolated circulating hematopoietic stem cells from patients with SLE to generate adherent ce...

Hadi Reihani, Mahmoud Mahmoudi, Maryam Rastin, Mohsen Ghoryani, Nafise Tabasi Shahrzad Zamani Taghizadeh Rabe Zahra Mirfeizi,

Objective(s):Genetic and environmental factors are involved in the pathogenesis of systemic lupus erythematosus (SLE). Autoreactive lymphocytes are cleared through apoptosis and any disturbance in the apoptosis or clearance of apoptotic cells may disturb tolerance and lead to autoimmunity. Vitamin D has anti-proliferative effects and controls cell cycle progression. In this study we investigate...

2012
Samar Erras Laila Benjilali Lamiaa Essaadouni

Periorbital edema occurs frequently in dermatomyositis, but it has rarely been noted in systemic systemic lupus erythematosus. We describe a patient who developed bilateral periorbital edema and erythema as the sole manifestation of systemic lupus erythematosus.

2016
Renee Fruchter Gibran Shaikh Kathryn L. Myers Narat J. Eungdamrong Hyun-Soo Lee Andrew G. Franks

EGR: erythema gyratum repens SLE: systemic lupus erythematosus INTRODUCTION Bullous lupus erythematosus is an autoantibodymediated subepidermal blistering disease that occurs in patients with systemic lupus erythematosus (SLE). Erythema gyratum repens (EGR) is a clinical diagnosis characterized by a wood grain pattern of centrifugally migrating erythematous plaques with fine leading scale. Alth...

2013
David S Pisetsky

the most seasoned and savvy clinician views lupus warily, considering it one of the most bewildering diseases in all of medicine. Th is situation should not be a surprise since the manifestations of lupus are dizzying in their variety and exasperating in their subtlety. Furthermore , although lupus has been at the heart of immuno-logy research for decades, investigators have yet to fi gure out ...

2013
Kentaro Isoda Tohru Takeuchi Shigeki Makino Toshiaki Hanafusa

We report a patient with systemic lupus erythematosus complicated by toluene poisoning. She had erythema, alopecia, arthralgia, and various neurological symptoms. Laboratory findings showed leukocytopenia, low levels of complements, and anti-dsDNA antibody. However, normal interleukin-6 level and IgG index of cerebrospinal fluid and brain magnetic resonance imaging and single photon emission co...

2017
Adrián Imbernón-Moya Elena Vargas-Laguna Fernando Burgos Eva Fernández-Cogolludo Antonio Aguilar-Martínez Miguel Ángel Gallego-Valdés

Annular urticarial lesions in a child must establish a main differential diagnosis with urticaria multiforme, common urticaria, acute hemorrhagic edema of infancy, erythema marginatum, erythema annulare centrifugum, annular erythema in childhood, erythema multiforme, Sweet's syndrome, Schönlein-Henoch purpura, erythematosus lupus, several systemic vasculitis, and serum sickness.

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