Synophthalmia is a form of cyclopia, in which some elements of two eyes are fused and form a single eye in the middle region of the forehead. The head of a Holstein female calf born from a 5-year-old cow was referred to Department of Pathology, School of Veterinary Medicine, Shahrekord University due to multiple congenital anomalies. The calf had been slaughtered immediately after birth due to ...

Macroscopic Analysis of Fetus Having Arhinencephaly, Synophthalmia and Holoprosencephaly Henriette Poaty1*, David Gentien2, Cecile Reyes2 and Jacques Silou3 1Laboratory of Histology, Embryology and Genetic Medical Faculty, BP 2672, University Marien Ngouabi, Brazzaville, Congo, Africa 2Plateforme Genomics, Department of Translational Research, 26 rue d’Ulm Institut Curie, 75005 Paris, France 3M...

An abnormal embryo (male of 465 mm total length) and 13 other embryos were removed from a pregnant female bull shark (Carcharhinus leucas) caught in coastal waters between the Grijalva River Terminos Lagoon southwestern Gulf Mexico. The first record synophthalmia leucism is presented. cyclopia case reviewed.

Synophthalmia is a form of cyclopia, in which some elements of two eyes are fused and form a single eye in the middle region of the forehead. The head of a Holstein female calf born from a 5-year-old cow was referred to Department of Pathology, School of Veterinary Medicine, Shahrekord University due to multiple congenital anomalies. The calf had been slaughtered immediately after birth due to ...

synophthalmia is a form of cyclopia, in which some elements of two eyes are fused and form a single eye in the middle region of the forehead. the head of a holstein female calf born from a 5-year-old cow was referred to department of pathology, school of veterinary medicine, shahrekord university due to multiple congenital anomalies. the calf had been slaughtered immediately after birth due to ...

Cyclopamine, a steroidal alkaloid from Veratrum californicum, is teratogenic causing a range of birth defects including cyclopia (synophthalmia) as well as other craniofacial and structural malformations. Previous studies have indicated that fetuses with cyclopia are smaller, under developed, and appear premature compared to gestational matched normal fetuses. Preliminary observations suggest t...

Ethanol has been described as a teratogen in vertebrate development. During early stages of brain formation, ethanol affects the evagination of the optic vesicles, resulting in synophthalmia or cyclopia, phenotypes where the optic vesicles partially or totally fuse. The mechanisms by which ethanol affects the morphogenesis of the optic vesicles are however largely unknown. In this study we make...