background: since tumors located in thorax region of body mainly move due to respiration, in the modern radiotherapy, there have been many attempts such as; external markers, strain gage and spirometer represent for monitoring patients’ breathing signal. with the advent of fluoroscopy technique, indirect methods were proposed as an alternative approach to extract patients’ breathing signals. ma...

PURPOSE We introduce a novel technique for analyzing tumor-motion surrogate signals using Empirical Mode Decomposition (EMD) and Hilbert-Huang Transformation (HHT). METHODS The tumor-motion surrogate signals were acquired (with RPM/Varian), from 20 lung-cancer patients in free-breathing method and its data were decomposed into Intrinsic Mode Functions (IMFs) using EMD. HHT was then applied to...

The purpose of this study was to evaluate the sliced body volume (SBV) as a respiratory surrogate by comparing with the real-time position management (RPM) in phantom and patient cases. Using the SBV surrogate, breathing signals were extracted from unsorted 4D CT images of a motion phantom and 31 cancer patients (17 lung cancers, 14 abdominal cancers) and were compared to those clinically acqui...

We present a method for organ motion compensation based on a statistical motion model. The novelty of our method is, that the surrogates for prediction can be independent of the model’s topology i.e. the surrogate signal does not have to correspond to a point of the motion model. By non-linear regression, we grasp the correlation between a captured signal during free breathing and the motion mo...

In this study we address the problem of predicting the position of a moving lung tumor during respiration on the basis of external breathing signals--a technique used for beam gating, tracking, and other dynamic motion management techniques in radiation therapy. We demonstrate the use of neural network filters to correlate tumor position with external surrogate markers while simultaneously pred...

1521 THE DIAGNOSIS OF SLEEP APNEA TYPICALLY INVOLVES AN OVERNIGHT POLYSOMNOGRAM WITH CONTINUOUS MONITORING OF SEVERAL PHYSIOLOGIC parameters and surrogate measures of airflow (nasal pressure [Pn], oronasal thermistor, expired CO2 waveform [PECO2]) using contact sensors. 1-5 A subject can come in contact with at least 20 such sensors during a study. These sensors and the wires can influence not ...

Sleep is associated with marked alterations in ventilatory control that lead to perturbations in respiratory timing, breathing pattern, ventilation, pharyngeal collapsibility, and sleep-related breathing disorders (SRBD). Mouse models offer powerful insight into the pathogenesis of SRBD; however, methods for obtaining the full complement of continuous, high-fidelity respiratory, electroencephal...

PURPOSE To investigate the effect of the marker placement on the correlation relationship between the motions of external markers and the internal target under different breathing patterns for several lung cancer patients. METHOD AND MATERIAL To monitor and record simultaneous motions of internal target and associated surrogate markers during respiratory gated radiotherapy, an infrared camera...

Primary Area Surrogate measures of safety ABSTRACT This paper describes the development of an in-vehicle measurement system that monitors the physiological signals (i.e., heart rate, heart rate variation, breathing and eye brinking) of drivers. These physiological signals will be utilized to detect the onset of driver fatigue, crucial for timely applying drowsiness countermeasures. Fatigue driv...

Breathing-induced location uncertainties of internal structures are still a relevant issue in the radiation therapy of thoracic and abdominal tumours. Motion compensation approaches like gating or tumour tracking are usually driven by low-dimensional breathing signals, which are acquired in real-time during the treatment. These signals are only surrogates of the internal motion of target struct...