A simple, rapid, and sensitive method for the detection of posaconazole using dispersive liquid-liquid microextraction (DLLME) coupled to surface-assisted laser desorption/ionization mass spectrometric detection (SALDI/MS) was developed. After the DLLME, posaconazole was detected using SALDI/MS with colloidal gold and α-cyano-4-hydroxycinnamic acid (CHCA) as the co-matrix. Under optimal extract...

In this work, two approaches based on Dispersive Liquid-Liquid MicroExtraction (DLLME) and Dispersive Liquid-Liquid MicroExtraction based on Solidification of Floating Organic Drop (DLLME-SFO) were compared for the extraction and preconcentration of crocin from saffron and biological samples. Different DLLME and DLLME-SFO parameters influencing the extraction efficiency were studied and opt...

dispersive liquid-liquid microextraction method (dllme) combined with high-performance liquid chromatography-ultraviolet detection (hplc-uv) was used to determine thiamine (b1), nicotinamide (b3) and pyridoxine (b6) in sour cherry juice. this method was rapid, simple and sensitive. separation was accomplished using a c18 column. the optimum chromatographic conditions were found to be: mobile ph...

A novel dispersive liquid-liquid microextraction (DLLME) method followed by HPLC analysis, termed sequential DLLME, was developed for the preconcentration and determination of aryloxyphenoxy-propionate herbicides (i.e. haloxyfop-R-methyl, cyhalofop-butyl, fenoxaprop-P-ethyl, and fluazifop-P-butyl) in aqueous samples. The method is based on the combination of ultrasound-assisted DLLME with in si...

dispersive liquid liquid microextraction (dllme) combined with gas chromatography–mass spectrometry (gc–ms) was used for the extraction and determination of 13 polycyclic aromatic hydrocarbons (pahs) in mineral water samples. in this procedure, the suitable combination of extraction solvent (500 µl chloroform) and disperser solvent (1000 µl acetone) were quickly injected into the water sample (...

A simple, fast and effective pre-concentration method for the determination of Cu (copper) and Ni (nickel) was developed using a Surfactant Assisted Dispersive Liquid-Liquid Microextraction (SA-DLLME) coupled by UV-Vis spectrophotometry in marine brown algae. The complexing agent was 1- (2- pyridylazo) – 2 - naphthol (PAN).The effects of various experimental parameters in the extraction ste...

The review of the RP HPLC analysis of basic psychotropic drugs is presented. It contains sample preparation methods with centrifugation, protein precipitation, liquid-liquid extraction (LLE), dispersive liquid-liquid microextraction (DLLME), solid-phase extraction (SPE), solid-phase microextraction (SPME), microwave-assisted extraction (MAE) and RP-HPLC analysis. Chromatographic behavior of bas...

background: a new microextraction method named dispersive liquid-liquid microextraction (dllme) for determination of chloroform in pool water and blood of swimmers after swimming is described. methods: this method was performed based on coupling dispersive liquid-liquid microextraction (dllme) with gas chromatog­raphy-mass spectrometry (gc-ms). methanol and trichloroethylenes were used as the d...

A new, simple, rapid, sensitive and environmentally friendly ultrasound-assisted emulsification dispersive liquid–liquid microextraction (UAE-DLLME) has been developed for trace nickel Ni(II) separation preconcentration in environmental samples prior to spectrophotometric determination. The proposed method based on using non-ionic water-soluble surfactant Triton X-114 (TX-114) as a disperser so...

This review aims to provide an overview of homogeneous liquid-liquid extraction (HLLE) and dispersive liquid-liquid microextraction (DLLME) methods and their potential use in inorganic analysis. Relevant applications to the determination of metal ions, metalloids and organometals are included. The phase separation mechanisms of these unconventional solvent extraction techniques are discussed. T...