background: prediction of interaction sites within the membrane protein complexes using the sequence data is of a great importance, because it would find applications in modification of molecules transport through membrane, signaling pathways and drug targets of many diseases. nevertheless, it has gained little attention from the protein structural bioinformatics community. methods: in this stu...

various statistical methods have been proposed in terms of predicting the outcomes of facing special factors. in the classical approaches,  making the probability distribution or known probability density functions is ordinarily necessary to predict the desired outcome. however, most of the times enough information about the probability distribution of studied variables is not available to the ...

in this paper, we present a new brain tissue segmentation method based on a hybrid hierarchical approach that combines a brain atlas as a priori information and a least-square support vector machine (ls-svm). the method consists of three steps. in the first two steps, the skull is removed and cerebrospinal fluid (csf) is extracted. these two steps are performed using the fast toolbox (fmrib's a...

structural repetitive subsequences are most important portion of biological sequences, which play crucial roles on corresponding sequence’s fold and functionality. biggest class of the repetitive subsequences is “transposable elements” which has its own sub-classes upon contexts’ structures. many researches have been performed to criticality determine the structure and function of repetitive su...

Establishment of rating curves are often required by the hydrologists for flow estimates in the streams, rivers etc. Measurement of discharge in a river is a time-consuming, expensive, and difficult process and the conventional approach of regression analysis of stage-discharge relation does not provide encouraging results especially during the floods. P

the aim of this work is to examine the feasibilities of the support vector machines (svms) and k-nearest neighbor (k-nn) classifier methods for the classification of an aquifer in the khuzestan province, iran. for this purpose, 17 groundwater quality variables including ec, tds, turbidity, ph, total hardness, ca, mg, total alkalinity, sulfate, nitrate, nitrite, fluoride, phosphate, fe, mn, cu, ...

objectives in order to increase the classification accuracy of airs, this study introduces a new hybrid system that incorporates a support vector machine into airs for diagnosing tuberculosis. background tuberculosis (tb) is a major global health problem, which has been ranked as the second leading cause of death from an infectious disease worldwide. diagnosis based on cultured specimens is the...

recently, tuning the weights of the rules in fuzzy rule-base classification systems is researched in order to improve the accuracy of classification. in this paper, a margin-based optimization model, inspired by support vector machine classifiers, is proposed to compute these fuzzy rule weights. this approach not only  considers both accuracy and generalization criteria in a single objective fu...