conclusions: the co-administration of saffron aqueous extract and safranal reduced toxic effects of safranal in acute and sub-acute toxicities. background: saffron and its constituents are widely used around the world as a spice and medicinal plant. different constituents in medicinal herbs are thought to have the potential to induce useful and/or adverse effects. so, efforts have been made to ...

objective(s):copper oxidenanoparticles have different industrial applications so it is inevitable that nanoparticulate products finally find their way into aquatic ecosystems. nevertheless there is little information available about their effects on some of edible fish. the present study aims to determine the acute toxicity and evaluate the effect of two sub-acute concentrations (50 and 70% 96 ...

background: exposure to any xenobiotic can disturb the metabolic activities of particular organs. hence present study is designed to find changes in hepatic biochemistry, histochemistry and histopathology besides serum enzyme levels after acute and sub-acute treatment with mercuric chloride, a heavy metallic compound, in albino rat (rattus norvegicus). materials & methods: thirty albino rats we...

Objective: This study was conducted to assess the toxicity profile of the aqueous-fermented extract of Musa paradisiaca in rats. Materials and Methods: In acute toxicity test, the rats of different groups were orally administered with a single dose of 500, 1000, 2000 and 5000 mg/kg of fermented extract of M. paradisiaca. The rats were monitored for behavioral changes, toxicity signs and mortali...

All aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. The high concentration levels, damage tissues and interfere with the normal growth and proliferation. The aim of this research was to Investigation acute toxicity of ZnSO4 and CuCl2 to Gambusia holbrooki ...

All aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. The high concentration levels, damage tissues and interfere with the normal growth and proliferation. The aim of this research was to Investigation acute toxicity of ZnSO4 and CuCl2 to Gambusia holbrooki ...

All aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. The high concentration levels, damage tissues and interfere with the normal growth and proliferation. The aim of this research was to Investigation acute toxicity of ZnSO4 and CuCl2 to Gambusia holbrooki ...

All aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. The high concentration levels, damage tissues and interfere with the normal growth and proliferation. The aim of this research was to Investigation acute toxicity of ZnSO4 and CuCl2 to Gambusia holbrooki ...

Introduction: Nonsteroidal anti-inflammatory drugs are the most commonly used drugs to reduce pain and inflammation. Aceclofenac is a newer derivative of diclofenac with less gastrointestinal complications. The objective of the present study was to evaluate the toxicity profile of sustain release aceclofenac injection in rats at three dose levels, ranging from 2 to 10 mg/kg body weight. Mater...

The REACH Regulation requires information on acute oral toxicity for substances produced or imported in quantities greater than one ton per year. When registering, animal testing should be used as last resort. The standard acute oral toxicity test requires use of animals. Therefore, the European Chemicals Agency examined whether alternative ways exist to generate information on acute oral toxic...