This work deals with the simultaneous estimation of metformin hydrochloride and pioglitazone hydrochloride in a bilayered tablet dosage form, without prior separation by two techniques. The methods employed are derivative spectrophotometery and Q analysis. The absorption maxima at 231 nm and 269 nm were used for the estimation of metformin and pioglitazone, respectively. Both the drugs and thei...

Neural tube defects (NTD) comprise of a group of congenital malformations that include spina bifida, anencephaly and encephalocele. Reports have implicated zinc deficiency as one of the causative factors of NTDs. We compared the serum zinc level of 23 newborns having neural tube defects with 35 healthy controls by spectrophotometery during 2003-2004. Zinc deficiency was documented in 43.5% of t...

Abstract Three different dosimetry systems were prepared based on diphenyl thiocarbazone (DTH) dye: polymer films made with, poly(vinyl alcohol), DTH liquid dosimeter and gel dosimeter. All the received several gamma doses. The three analyzing by UV–Vis spectrophotometery before after irradiation. effective dose range in linear part of these is between 1–10 kGy, 0.3–2 50–200 Gy. dosimeters reli...

in this work, a new spectrophotometric method for the determination of trace amount of cobalt (іі) ionwas investigated and the stability constant of the related complex was evaluated 2.174 × 104. in the cobalt(іі)-piroxicam complex, the maximum absorbance wavelength is 570 nm and the linearity of calibrationcurve was investigated (5-10 ppm). the relative standard deviation for seven replicate e...

this study describes a new simple, sensitive and selective catalytic kinetic spectrophotometricmethod for the determination of vanadium (v). the method is based upon the catalytic effect ofvanadium (v) on the oxidation of carminic acid by bromate in sulfuric acid media. the reaction wasfollowed spectrophotometrically by measuring the decrease in absorbance at 490 nm and thedependence of sensiti...

In this study, total crocin was extracted from saffron stigmas using crystallization method. Ethanol 80% was selected as the best extraction solvent. Crystallization process was carried out in one and two steps at different temperatures. Ethanol 80% was used as crystallization medium. Crocin crystals obtained from the first crystallization had low purity and thus were subjected to the second cr...

Article history: Received on: 15/10/2012 Revised on: 06/12/2012 Accepted on: 08/01/2013 Available online: 28/01/2013 In this study zero, first and second order derivative spectrophotometric method were developed for the estimation of sitagliptine. In zero order spectrophotometery, absorbance value was measured at 267nm. In first derivative spectrophotometry amplitudes were measured at 213nm. In...