It has been hypothesized that soy isoflavones exhibit anti-oxidative and anti-inflammatory functions, however, the effects of soy isoflavones on inflammatory bowel diseases remain unknown. Therefore, the present study aimed to investigate the effect and underlying mechanism of dietary soy isoflavones on dextran sulfate sodium (DSS)-induced colitis. Mice were administered DSS and soy isoflavones...

BACKGROUND AND AIMS The substantial characteristics of Irritable Bowel Syndrome (IBS) are associated with estrogens in women. Both soy isoflavones and vitamin D can modulate estrogen receptors in the colonic smooth muscles. The aim of this study was to investigate the effects of soy isoflavones, vitamin D and their probable interactions in women with IBS. METHODS In a factorial blinded random...

the aim of this research was to perform a systematic review of the efficacy of non-hormonal herbal drugs in the treatment of vaginal atrophy in postmenopausal women. three electronic databases were systematically searched from their inception to may2015: pubmed, cochrane library (cochrane central register of controlled trials) and scopus. in this meta-analysis, vaginal maturation value was cons...

We previously showed that genistein, the major bioactive component of soy isoflavones, acts as a radiosensitizer and potentiates prostate tumor cell killing by radiation in vitro and in animal tumor models in vivo. However, when given alone in vivo, pure genistein promoted increased lymph node metastasis, which was not observed with a soy isoflavone mixture consisting of genistein, daidzein, an...

OBJECTIVES To determine the effects of isoflavones (soy phyto-estrogens) on serum total cholesterol (TC), low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL) and triglyceride (TG). METHODS We searched electronic databases and included randomized trials with isoflavones interventions in the forms of tablets, isolated soy protein or soy diets. Review Manager 4....

Soy protein and isoflavones (phytoestrogens) have gained considerable attention for their potential role in improving risk factors for cardiovascular disease. This scientific advisory assesses the more recent work published on soy protein and its component isoflavones. In the majority of 22 randomized trials, isolated soy protein with isoflavones, as compared with milk or other proteins, decrea...

Prostate cancer is the most frequently diagnosed form of cancer and the second leading cause of cancer related deaths in the United States. Increased consumption of soy is thought to reduce the risk for this disease. More specifically, the isoflavones found in soy are responsible, in part, for these anticancer effects. Isoflavones are organic compounds found in soy and other legumes and it is t...

Isoflavones are thought to have an important role in the prevention of hormonerelated diseases. This study was undertaken to identify the profile of urinary isoflavone metabolites collected within 24 h after the consumption of unfermented or fermented soy foods. The proportions of b-glycosides and aglycones to total isoflavone intake were much higher in soybean paste than soy flour. Twenty urin...

PURPOSE/OBJECTIVES To present state-of-the-art information about the risks and benefits of soy isoflavones for breast cancer survivors. DATA SOURCES Published research articles, pertinent articles and books, and computerized databases. DATA SYNTHESIS Some epidemiologic data suggest that soy isoflavones play an important role in preventing breast cancer in Asian women and promoting women's h...

Isoflavones are major phenolic compounds found in soybeans and soy-based foods. Healthbeneficial functions of soy foods are closely associated with these phytoestrogenic compounds. Twelve chemical forms of isoflavones are found in soybeans including three aglycones (genistein, daidzein, and glycitein), and their corresponding conjugated β-glucosides, 6''-O-acetyl-βglucosides, or 6''-O-malonyl-β...