نتایج جستجو برای: Solid lipid nanoparticle (SLN)

تعداد نتایج: 377311  

Journal: :Journal Of Mechanical Engineering, Science, And Innovation 2022

Solid Lipid Nanoparticle (SLN) merupakan sistem koloid pembawa untuk mengontrol perbaikan susunan kimia tubuh. SLN dapat meningkatkan kelarutan obat yang memiliki rendah dalam air dan juga pelepasan. Tujuan dari penelitian ini adalah melakukan analisis bibliometrik terhadap pengembangan sebagai drugs delivery dengan menggunakan pemetaan software VOSviewer. Data digunakan diperoleh dikumpulkan P...

Journal: :iranian journal of basic medical sciences 0
bahman khameneh department of food and drug control, mashhad university of medical sciences, mashhad, iran vahid halimi school of pharmacy, mashhad university of medical sciences, mashhad, iran mahmoud reza jaafari biotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran shiva golmohammadzadeh nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): in the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (sln)-safranal formulations were evaluated. materials and methods:series of sln were prepared using glyceryl monostearate, tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (hph) methods. sln formulations were characterized ...

2011
Jifu Hao Xinsheng Fang Yanfang Zhou Jianzhu Wang Fengguang Guo Fei Li Xinsheng Peng

The purpose of the present study was to optimize a solid lipid nanoparticle (SLN) of chloramphenicol by investigating the relationship between design factors and experimental data using response surface methodology. A Box-Behnken design was constructed using solid lipid (X(1)), surfactant (X(2)), and drug/lipid ratio (X(3)) level as independent factors. SLN was successfully prepared by a modifi...

Background: Interferon (IFN) are small proteins that belong to the cytokine family and may interfere with viral infections and some cancers. There are many studies focused on the PEGylated interferon’s bioactivity. In this study, we used solid lipid nanoparticles (SLNs) to produce new drug formulations, with the aim of reducing costs, increasing effectiveness, and also reducing side effects, an...

Journal: :iranian journal of pharmaceutical research 0
golnar dorraj department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. hamid reza moghimi department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran.

abstractvarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (slns). due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. different strategies have been employed to overcome this problem. in this direction, the present study introduces erodible in-situ forming gel systems ...

Objective(s): In the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. Materials and Methods:Series of SLN were prepared using glyceryl monostearate, Tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (HPH) methods. SLN formulations were characterized ...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2014
Hibah M Aldawsari Abeer Hanafy Gihan S Labib Jihan M Badr

The antihyperglycemic activity of the extracts and preparations of solid lipid nanoparticle suspensions of two mistletoes growing in Saudi Arabia, Plicosepalus acaciae and P. curviflorus, as well as their possible antioxidant effect were investigated in a type 2 diabetic animal model. Type 2 diabetes was induced in adult male Wistar rats by a high-fat diet followed by injection of streptozotoci...

Low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (LMWH-ISL-SLN) was developed for injective application. The morphological observation, particle diameter and zeta potential of LMWH-ISL-SLN were characterized using transmission electron microscopy (TEM) and a Malvern Zetasizer. Its entrapment efficiency (EE) and drug loading (DL) were determined by ultracen...

Journal: :iranian journal of pharmaceutical research 0
xiaoyun zhang school of pharmacy, lanzhou university, lanzhou, 730000, china, r.o.c. hua qiao drug clinical trial institution, the first hospital of lanzhou university ying chen school of pharmacy, lanzhou university lin li school of pharmacy, lanzhou university huxiong xia department of pharmaceutics, the first hospital of lanzhou university yanbin shi school of pharmacy, lanzhou university

low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (lmwh-isl-sln) was developed for injective application. the morphological observation, particle diameter and zeta potential of lmwh-isl-sln were characterized using transmission electron microscopy (tem) and a malvern zetasizer. its entrapment efficiency (ee) and drug loading (dl) were determined by ultracen...

Low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (LMWH-ISL-SLN) was developed for injective application. The morphological observation, particle diameter and zeta potential of LMWH-ISL-SLN were characterized using transmission electron microscopy (TEM) and a Malvern Zetasizer. Its entrapment efficiency (EE) and drug loading (DL) were determined by ultracen...

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