Inhibition of 3':5'-cyclic-AMP-5'-nucleotidohydrolase (EC 3.1.4.17) type II (cAMP-phosphodiesterase) by sodium molybdate was studied: While determination of inorganic phosphate and 5'-ribonucleotide phosphohydrolase (5'-nucleotidase) (EC 3.1.3.5) activity was not disturbed by sodium molybdate in concentrations up to 10 mM, cAMP-phosphodiesterase was inhibited by millimolar concentrations of mol...

We have recently purified the modulator of the glucocorticoid-receptor complex from rat liver. Purified modulator inhibits glucocorticoid-receptor complex activation and stabilizes the steroid-binding ability of the unoccupied glucocorticoid receptor. Since these activities are shared by exogenous sodium molybdate, modulator appears to be the endogenous factor that sodium molybdate mimics. In t...

This study aims to evaluate the benefit of combined administration of sodium molybdate with atorvastatin in management of hyperlipidemia. Hyperlipidemic male Serian golden hamsters were administered either atorvastatin (40 or 80 mg/kg, p.o.) sodium molybdate (100 mg/kg, p.o.) or combination of atorvastatin (40 mg/kg, p.o.) with sodium molybdate (100 mg/kg, p.o.) for 30 consecutive days. Blood l...

As a result of a widespread application in numerous industrial processes, chromium is a contaminant of many environmental systems. Chromium and their compounds are toxic to both invertebrates and vertebrates and, for this reason, there has been a search for suitable and less toxic alternatives. Molybdenum compounds have been studied as alternative to chromium compounds for some industrial appli...

A facile, efficient, simple, environmentally safe, regioselective, controllable and economical method for the oxybromination of aromatic compounds using sodium molybdate in presence of mineral acids and H2O2. The use of sodium molybdate as catalyst accelerates the rate of reaction in presence of mineral acids and hydrogen peroxide.

Contradictory findings on the effects of sodium molybdate on estrogen receptor activation have been recently reported. In a preliminary report (Mauck, L. A., and Notides, A. C. (1980) Proceedings of the 62nd Annual Meeting of the Endocrine Society, Abstr. 209) it was suggested that sodium molybdate prevents heat activation of the calf uterine estrogen receptor. This effect was reversible upon d...

I . The oral administration of sodium molybdate caused a rapid rise of molybdenum in the milk of cows and goats fed on a low-molybdenum diet, but did not affect the xanthine oxidase activities of the milk of either species. 2. In the milks of cows not dosed with sodium molybdate, the regression of the xanthine oxidase activity ( y ) on the molybdenum content (x) was found to be (r = +0.9386; P ...

Because sodium molybdate stabilizes steroid receptors, this compound has been included in the homogenizing medium in order to maximize the recovery of measurable steroid receptors in normal and neoplastic tissues. This study demonstrates that sodium molybdate extracts additional androgen receptors from prostatic nuclei in a concentration-dependent manner. Nuclei previously washed with Triton X-...

In previous work, we reported the growth of well-structured single-walled carbon nanotubes (SWNT) by CO disproportionation on Co:Mo/SiO2 catalysts. We have proposed that high SWNT selectivity can only be obtained when most of the Co in the sample is interacting with Mo and forming a cobalt–molybdate surface layer. In this contribution, we report further evidence to the hypothesis by an investig...