OBJECTIVE Sodium hypochlorite (NaOCl) is a common antimicrobial and tissue-dissolving irrigant. The aim of this in vitro study is to evaluate and compare dissolution capacities of sodium hypochlorite solutions after electrically activation (E-NaOCl) on bovine muscle specimens at various time periods and concentrations. MATERIALS AND METHODS Three sodium hypochlorite solutions of 1.25%, 2.5%, ...

INTRODUCTION This study investigated the inhibition of the antimicrobial activity of sodium hypochlorite (NaOCl) by bovine serum albumin (BSA). The killing of Enterococcus faecalis, Candida albicans, Staphylococcus epidermidis, and Escherichia coli by NaOCl in concentrations from 2% to 0.03% was measured in the presence of BSA in concentrations between 6.7% and 0.1%. METHODS NaOCl, BSA, and m...

Sodium hypochlorite (NaOCl) is the active ingredient in household bleach and is commonly used as a disinfectant to clean equipment contaminated by the amphibian pathogen Batrachochytrium dendrobatidis (Bd) in lab husbandry and field studies. We conducted a series of replicated exposure trials using a single Global Pandemic Lineage Bd isolate from Panama (JEL 310) and concentrations of NaOCl ran...

Introduction As the root canal system considered to be complex and unpredictable, using root canal irrigants and medicaments are essential in order to enhance the disinfection of the canal. Sodium hypochlorite is the most common irrigant in endodontics. Despite its excellent antimicrobial activity and tissue solubility, sodium hypochlorite lacks some important properties such as substantivity a...

The purpose of this study was to assess the effectiveness of endodontic irrigants in removing the smear layer from instrumented root canal walls using Scanning Electron Microscopy (SEM). The endodontic irrigants used were: 1% sodium hypochlorite (NaOCl); 1% NaOCl mixed to 17% EDTAC; 2% chlorhexidine gel; and Ricinus communis gel. Photomicrographs of the middle and apical thirds were evaluated w...

Introduction: The purpose of this study was to compare the antibacterial effect of sodium hypochlorite gel and solution on Enterococcus faecalis (E. faecalis). The main purpose of a root canal treatment is to eliminate the bacteria and their products. Sodium hypochlorite solution has excellent antibacterial properties, but also some negative features. Materials and methods: Fifty six single...

AIM To evaluate and compare the cytotoxicity of various concentrations of sodium hypochlorite on immortalized human bone marrow mesenchymal stem cells (MSCs). MATERIALS AND METHODS The 5.25 percent sodium hypochlo-rite (NaOCl) at concentrations of 0.5, 0.1, 0.025, 0.0125, and 0.005 mg/ml were used to assess the cytotoxic effect on MSCs. Immortalized human bone marrow mesenchymal stem cells (h...

INTRODUCTION Root canal irrigants play a significant role in the elimination of microorganisms, tissue dissolution, and the removal of debris and smear layer. No single solution is able to fulfill these actions completely; therefore, their association is required. The aim of this investigation was to review the antagonistic interactions occurring when sodium hypochlorite (NaOCl), chlorhexidine ...

Chlorine is usually combined with inorganic compounds, such as sodium or calcium, to produce hypochlorites, which are effective disinfectants. Chlorine mixed with sodium is a liquid bleach known as sodium hypochlorite NaOCl. Chlorine mixed with calcium is usually in granular or tablet form and is called calcium hypochlorite Ca(OCL)2. Chlorine may also be available as chlorine dioxide (ClO2). Ho...