The noctuid, Helicoverpa armigera, is the most important crop pest worldwide. We evaluated the biological activity of soybean trypsin inhibitor and plant lectins against this pest to identify toxin genes for deployment through transgenic plants. Of the seven plant lectins tested, chickpea and snowdrop lectins showed marked antibiotic effects in terms of insect survival and development. Larval s...

The biosynthesis and processing of the Galanthus nivalis agglutinin were studied in vivo in ripening snowdrop ovaries. Using labeling and pulse chase labeling experiments it could be demonstrated that the snowdrop lectin is synthesized as a precursor of relative molecular weight (M(r)) 15,000 which is posttranslationally converted into the authentic lectin polypeptide of M(r) 13,000 with a half...

Giant Snowdrop (Galanthus elwesii Hook) is a species of snowdrop belonging to the Amaryllidaceae family. In this study, deformation rates bulbs was calculated as % (percent). For sterilization G. were sterilized at different concentrations (1, 3, 5, 7, 9, 11 and 13 %) sodium hypochlorite (NaOCl) for 10, 15, 20, 25 minutes. The rinsed with sterile distilled water 3 times 5 minutes then transferr...

A new mannose-specific plant lectin (GNA) isolated from the snowdrop bulb was immobilized on Sepharose 4B and employed for the purification of certain glycoproteins with high-mannose type glycan chains. Murine IgM bound tightly to this column and was eluted with 0.1 M methyl alpha-D-mannoside whereas bovine and murine IgG were not bound. When a murine hybridoma serum containing IgM monoclonal a...

Galantamine is a natural product belonging to the isoquinoline alkaloid family of compounds. It was first discovered and isolated in the 1950s from Galanthus nivalis (common snowdrop) and Galanthus woronowii (Caucasian snowdrop), members of the Amaryllidaceae family (Marco and do Carmo Carreiras, 2006). Alzheimer’s disease (AD) is named after Dr. Alois Alzheimer, who first identified the diseas...

Poly(A)-rich RNA isolated from ripening ovaries of snowdrop (Galanthus nivalis L.) yielded a single 17-kDa lectin polypeptide upon translation in a wheat-germ cell-free system. This lectin was purified by affinity chromatography. Translation of the same RNA in Xenopus leavis oocytes revealed a lectin polypeptide which was about 2 kDa smaller than the in vitro synthesized precursor, suggesting t...

An increase in life expectancy creates prerequisites for the appearance of more patients with cognitive impairments. Early diagnosis, treatment and rehabilitation disorders improves quality patients, prevents development dementia, is great social importance. Herbal medicines are highly effective mild moderate impairment, affect various links pathogenesis, have minor side effects. The most them ...