background university of pennsylvania smell identification test (upsit) is one of the most common smell identification tests to assess olfactory function. objectives the study was conducted to assess the accuracy of university of pennsylvania smell identification test (upsit) in iranian population. materials and methods university of pennsylvania smell identification test was performed on 30 (5...

Smell dysfunction is a common and underdiagnosed medical condition that can have serious consequences. It is also an early biomarker of neurodegenerative diseases, including Alzheimer's disease, where olfactory deficits precede detectable memory loss. Clinical tests that evaluate the sense of smell face two major challenges. First, human sensitivity to individual odorants varies significantly, ...

Smell identification deficits exist in schizophrenia, and may be associated with its negative symptoms. Less is known about smell identification and its clinical correlates in individuals at clinical high risk (CHR) for schizophrenia and related psychotic disorders. We examined smell identification, symptoms and IQ in 71 clinical high-risk (CHR) subjects and 36 healthy controls. Smell identific...

PURPOSE To evaluate nasal mucus levels of cAMP and cGMP in patients with taste and smell dysfunction with respect to severity of their smell loss. METHODS cAMP and cGMP were measured in nasal mucus using a sensitive spectrophotometric 96 plate ELISA technique. Smell loss was measured in patients with taste and smell dysfunction by standardized psychophysical measurements of olfactory function...

Artificially reproducing smell sensations, without using chemical odorants, would change the future multisensory internet experiences. This article presents a computer-controlled reproduction technology proposed for stimulating human olfactory receptors, weak electric pulses. We developed concept prototype that can generate rectangular-shaped electrical pulses in different frequencies (0–30 kHz...

The urinary excretion of (an) odorous substance(s) after eating asparagus is not an inborn error of metabolism as has been supposed. The detection of the odour constitutes a specific smell hypersensitivity. Those who could smell the odour in their own urine could all smell it in the urine of anyone who had eaten asparagus, whether or not that person was able to smell it himself. Thresholds for ...

Background/Aims Patients with gastroparesis and gastroesophageal reflux disease (GERD) often report decreased enjoyment when eating. Some patients remark that food does not smell or taste the same. To determine if taste and/or smell disturbances are present in patients with gastroparesis and/or GERD and relate these to gastrointestinal symptom severity. Methods Patients with gastroparesis and...

If any sense modality represents, vision does, but argument is needed to show that smell does. This paper rebuts two reasons for doubting that smell represents, and offers several arguments that it does. The paper then considers several recent proposals as to exactly what a smell represents, and defends a version of the author's original proposal-that a smell represents a miasma in the air-agai...