BACKGROUND It has been reported that systemic administration of allopurinol improves cell survival. This study was aimed to evaluate effects of allopurinol on skin flaps in dogs. METHODS Twenty dogs underwent one skin flap surgery with a 2-week interval. The first procedure was performed according to the standard protocols. The second phase was started by a 1-week pretreatment with all...

background it has been reported that systemic administration of allopurinol improves cell survival. this study was aimed to evaluate effects of allopurinol on skin flaps in dogs. methods twenty dogs underwent one skin flap surgery with a 2-week interval. the first procedure was performed according to the standard protocols. the second phase was started by a 1-week pretreatment with allopurinol....

despite all modern surgical techniques, skin flap that is considered as the main method in most reconstructive surgeries puts the skin tissue at danger of necrosis and apoptosis derived from ischemia. therefore, finding a treatment for decreasing the apoptosis derived from flap ischemia will be useful in clinic. in present study, we evaluated the effect of azelaic acid 20% and finasteride on ex...

background mainstay of post-burn reconstruction is release and split skin grafting. pedicle flaps are cumbersome to the patient, require multiple procedures and hospitalization. free flaps are technically demanding and facilities are not universally available. here we evaluated the local perforator flaps for post-burn reconstruction. methods we have used sixteen perforator propellar flaps for p...

We have devised a technique of two-stage tracheal reconstruction using S-shaped skin flaps and an aural conchal cartilage graft. During the first operation, S-shaped skin flaps were elevated before resection of the trachea. A tracheocutaneous fistula was created at the tracheal defect using S-shaped skin flaps while placing the conchal cartilage graft underneath. During the second operation, a ...

BACKGROUND Mainstay of post-burn reconstruction is release and split skin grafting. Pedicle flaps are cumbersome to the patient, require multiple procedures and hospitalization. Free flaps are technically demanding and facilities are not universally available. Here we evaluated the local perforator flaps for post-burn reconstruction. METHODS We have used sixteen perforator propellar flaps fo...

Objective. The influence of Coherent Ultrapulse, TruPulse and Erbium: YAG laser skin resurfacing on survival of the skin flaps when performed simultaneously was evaluated. Material and methods. We used twelve female Yucatan minipigs in the study. Skin flaps including paniculus carnosus were raised on the animals’ back. The flaps were sutured into the defect under tension. We designed 4 experime...

The effects of hyperbaric air and oxygen on skin survival were studied in acute 8 X 8 cm neurovascular island flaps in rats. Skin flaps treated with hyperbaric 8% oxygen (equivalent to room air at standard pressure) exhibited no improvement in skin survival. Skin flaps treated with hyperbaric air (21% oxygen) and hyperbaric 100% oxygen exhibited significant increases in survival.

conclusions scarring of the neck produces problems with function, and appearance. in our view, the supraclavicular flap, a thin flap of good texture, is an excellent and highly reliable flap for covering defects of the anterior neck. this flap is easy to harvest, with good functional and aesthetic results. results thirty-seven of the 41 flaps survived completely, but there were three cases of d...

BACKGROUND This study presents an alternative in reconstruction, using free skin flaps in combination with pedicled mandible bone flaps for complex lateral mandibular defects. METHODS In all, 13 patients were included in this prospective study. Pedicled mandible myo-osseous flaps were used for reconstruction of bone defects of the lateral mandible in combination with free skin flaps, includin...