OBJECTIVES To gain a more detailed understanding of endogenous (mutational) and exogenous (horizontally acquired) resistance to silver in Gram-negative pathogens, with an emphasis on clarifying the genetic bases for resistance. METHODS A suite of microbiological and molecular genetic techniques was employed to select and characterize endogenous and exogenous silver resistance in several Gram-...

Sütterlin, S. 2015. Aspects of Bacterial Resistance to Silver. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1084. 64 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9205-2. Bacterial resistance to antibiotics has increased rapidly within recent years, and it has become a serious threat to public health. Infections caused by multi-drug resist...

Silver-based dressings have been used extensively in wound management in recent years, but data on their antimicrobial activity in the clinical setting are limited. In order to explore their effects on chronic leg ulcer flora, 14 ulcers were cultured after at least 3 weeks treatment with Aquacel Ag(®) or Acticoat(®). Phenotypic and genetic silver resistance were investigated in a total of 56 is...

this laboratory study simultaneously was conducted to evaluate the resistance to heavy metals, silver, cadmium and a number of commonly used antibiotics. sampling was done in 2014 of the two silver workshops in isfahan, and the inlet of phase 2 of shahin shahr wastewater treatment plant, isfahan. to isolate resistant bacteria to metal silver and cadmium and review multiple resistance to other m...

Ionic silver exhibits antimicrobial activity against a broad range of micro-organisms. As a consequence, silver is included in many commercially available healthcare products. The use of silver is increasing rapidly in the field of wound care, and a wide variety of silver-containing dressings are now commonplace (e.g. Hydrofiber dressing, polyurethane foams and gauzes). However, concerns associ...

UNLABELLED Silver nanoparticles are well known potent antimicrobial agents. Although significant progresses have been achieved on the elucidation of antimicrobial mechanism of silver nanoparticles, the exact mechanism of action is still not completely known. This overview incorporates a retrospective of previous reviews published and recent original contributions on the progress of research on ...

This laboratory study simultaneously was conducted to evaluate the resistance to heavy metals, silver, cadmium and a number of commonly used antibiotics. Sampling was done in 2014 of the two silver workshops in Isfahan, and the inlet of phase 2 of Shahin Shahr wastewater treatment plant, Isfahan. To isolate resistant bacteria to metal silver and cadmium and review multiple resistance to other m...

Silver is considered as antibacterial agent with well-known mode of action and bacterial resistance against it is well described. The development of nanotechnology provided different methods for the modification of the chemical and physical structure of silver, which may increase its antibacterial potential. The physico-chemical properties of silver nanoparticles and their interaction with livi...

Limited antibacterial activity of silver ions leached from silver-impregnated food contact materials could be due to: 1) the presence of silver resistance genes in tested bacteria; or 2) lack of susceptibility to silver ion-mediated killing in the bacterial strain (K. Williams, L. Valencia, K. Gokulan, R. Trbojevich, S. Khare, 2016 [1]). This study contains data to address the specificity of si...

Silver first gained regulatory approval for use as an antimicrobial agent in the early 20th century, but its usage diminished with the introduction of antibiotics in the 1940s. Recently, however, topical silver has gained popularity once again, principally in the management of open wounds. This has been largely due to the spread of methicillin-resistant Staphylococcus aureus and the resultant r...