results sickle cells were observed among 20% of subjects with the dilution of 1:50 and 70% of subjects with the dilution of 1:100. mean percentage of sickle red cells with dilutions of 1:50, 1:100 and 1:200 were 3.75%, 25.75% and 43.0%, respectively. conclusions it is suggested that c. fistula may protect rbc against sickling, in hypoxic conditions, in individuals with hbs gene defect. objectiv...

abstract background prevalence of hereditary blood diseases such as sickle cell anemia, sickle thalassemia and thalassemia major are high in khuzestan province. sickle cell anemia and beta-thalassemia are predominantly common in iranian arabs. pulmonary complications account for a large proportion of morbidity and mortality in patients with and sickle cell disease. periodic lung function assess...

background: children affected with sickle cell disease (scd) are at increased risk for severe morbidity and mortality, especially during the first 3-5 years of life. it is suggested that early treatment can improve the condition. the aim of this pilot study was to estimate the incidence of hemoglobin s (hbs) by umbilical cord blood screening in khorramshahr and abadan cities in southwest of ira...

conclusions the results of this study showed that self-management interventions are effective in promoting self-efficacy in patients with sickle cell disease. thus, the use of self-management programs is advisable to change behaviors and promote self-efficacy in such patients. background patients with sickle cell disease suffer from various complications during their lifetime. in order to cope ...

background: studies have demonstrated that sickle cell trait can be found in an asymptomatic healthy carrier with normal complete blood count (cbc) and red blood cell (rbc) indices. according to iranian ministry of health bulletin instructions, prenuptial thalassemia screening program (tsp) primarily depends on rbc indices which are measured through a routine cbc. only when these levels are bel...

background: hemoglobin s arises is the result of a point mutation (a-t) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. the presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...

Abstract Background Prevalence of hereditary blood diseases such as sickle cell anemia, sickle thalassemia and thalassemia major are high in Khuzestan province. Sickle cell anemia and beta-thalassemia are predominantly common in Iranian Arabs. Pulmonary complications account for a large proportion of morbidity and mortality in patients with and sickle cell disease. Periodic lung function asse...

Background: Hemoglobin S arises is the result of a point mutation (A-T) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. The presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...

Abstract Background: Transcranial Doppler ultrasonography results have not been previously studied in among Iranian sickle cell anemia patients. The present study was performed to evaluate the pattern of intracranial flow velocities among Iranian children with sickle cell anemia and the hematological parameters that can affect the time-averaged mean of maximum velocity in major intracranial...