This paper reports a preparation method for silk sericin hydrogel using the Sericin-hope silkworm, whose cocoons consist almost exclusively of sericin. Sericin solution, prepared from Sericin-hope cocoons, contains intact sericin and forms elastic hydrogels with the addition of ethanol. The sericin hydrogel can be prepared without crosslinking by chemicals or irradiation and might be usable as ...

Recent efforts have focused on the use of sericin proteins extracted from cocoons of silkworm as a healthy food source for human consumption. In this study, we focused on the antioxidative properties of sericin proteins. The antioxidative properties were measured in sericin proteins extracted from the shell of the cocoon, designated hereafter as white sericin protein and yellow-green sericin pr...

This study was conducted to assess protective effect of an antioxidant protein, sericin, on tumor promotion in the 7,12-dimethylbenz (alpha) anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol 13-acetate (TPA)-promoted mouse skin tumorigenesis model. In experiment 1, sericin was applied topically to DMBA-initiated female ICR mouse skin at the doses of 2.5 and 5 mg twice per week for 16 we...

Fatty-acylated sericin {1:0.7 molar ratio of sericin (Mr 18,700) to oleic acid} was prepared by lipase-catalyzed solid-phase synthesis in n-hexane containing oleic acid to endow sericin with interfacial properties. Acylation with oleic acid was confirmed by 1H-NMR. The fatty-acylated sericin exhibited superior emulsifying activity index and emulsion stability in the presence of 0-0.5 M NaCl, in...

Approximately half of the transplantable pancreatic islet tissue is lost during isolation, including the digestion and purification steps. Modifying the isolation method could increase the yield. This would enable the one donor-one recipient concept and improve the therapeutic effects of islet transplantation. This study aims to improve islet transplantation by increasing the yield of islets fr...

Int. J. Indust. Entomol. Vol. 27, No. (1), pp. 180-184 (2013) 180 181 The dry mass of sericin and cocoons was determined using a moisture analyzer (XM60, Precesa, Switzerland). Rheological measurement were performed on 1) the 0.3% (w/ v) sericin aqueous solutions, 2) sericin gels prepared from the 0.3% sericin solution, and 3) frozen and thawed sericin gels. The steady-state flow of sericin sol...

Silk is made up of two types of proteinssilk fibroin and sericin. Silk sericin is the main residue (≈2030%) in raw silk fiber. It is composed of 18 amino acids. Solubility, molecular weight, and gelling properties of sericin depends on the methods of isolation i.e. degumming. Sericin has proved itself as a highly potential biomaterial by wide variety of applications in medicine, pharmaceuticals...

Sericin is a highly hydrophilic protein family acting as the glue in Bombyx mori silk. In order to apply sericin as a wound dressing, a novel sericin film named gel film was prepared by a simple process without using any chemical modifications: sericin solution was gelled with ethanol into a sheet shape and then dried. Infrared analysis revealed that the sericin gel film contained water-stable ...

This study was done to discover tbe underlying mechanism of the inhibitory effect of sericin against colon tumorigenesis. Mice were fed a diet with 30 g!kg sericin for 115 d, and giyen a weekly iajection of 1,2dimethylhydrazine (10 mglkg body weight) for the initial 10 wk. Dietary supplemental sericin caused a 62% reduction in the incictence of colonic adenoma (P<O.05), but did not affect the i...

Wound healing is a biological process directed to the restoration of tissue that has suffered an injury. An important phase of wound healing is the generation of a basal epithelium able to wholly replace the epidermis of the wound. A broad range of products derived from fibroin and sericin from Bombyx mori silk are used to stimulate wound healing. However, so far the molecular mechanism underly...