of ill vitro release testing as a QA tool to ensure batch-to-batch uniformity has been gaining both increasing popularity and contempt in the pharmaceutical industry. Regardless of views and opinions, it is worthwhile to be prepared to conduct such studies if necessary. Currently, the most publicized methods use horizontal ("Franz or Modified Franz") diffusion cells, with an artificial support ...

The use of two semisolid media (semisolid Rappaport and semisolid Rappaport-Vassiliadis) for the isolation of Salmonella spp. from coastal waters was compared with the use of conventional media. Two hundred and fifty six samples were studied; Salmonella spp. were detected in 83. The semisolid media were the most sensitive, detecting 73 samples instead of the 53 detected by the conventional medi...

Semisolid processing is one of the modern routes in sound and near net shape parts production.  Preparation of semisolid slurry using a cooling slope is increasingly becoming popular, primarily because of its simplicity in design and ease of control of the process. In this research, the microstructures of Al6061 semisolid alloy cast via a miniature cooling slope were investigated. The propertie...

Systematic experimental work and modeling efforts have been conducted to characterize the yield behavior of commercial aluminum alloys in the semisolid state. In this study, extensive compression experiments were performed to measure the yield stress of semisolid aluminum slurries at high solid fractions (0.5 to 1.0), and a cone penetration method was employed to measure yield stress at low sol...

application of shearing during solidification to produce a non-dendritic semisolid slurry that can be Semisolid metal (SSM) processing is a relatively transferred directly into a mould or die to give a final new technology for metal forming. Different from product. Thixoforming is used to describe the near the conventional metal forming technologies which use either solid metals (solid state ne...

PURPOSE This study examines the relationship between quantitative magnetization transfer (qMT) parameters and the molecular composition of a model lamellar liquid crystal (LLC) system composed of 1-decyl alcohol (decanol), sodium dodecyl sulfate (SDS), and water. METHODS Samples were made within a stable lamellar mesophase to provide different ratios of total semisolid protons (SDS + decanol)...

Our results show that all of the brown rot fungi tested produce oxalic acid in liquid as well as in semisolid cultures. Gloeophyllum trabeum, which accumulates the lowest amount of oxalic acid during decay of pine holocellulose, showed the highest polysaccharide-depolymerizing activity. Semisolid cultures inoculated with this fungus rapidly converted C-labeled oxalic acid to CO(2) during cellul...

Semisolid powder processing (SPP) is a promising approach for near net-shape forming of features in micro/meso-scale. By combining the concept of forming in the semisolid state and conventional powder metallurgy, SPP provides a novel solution to various processing and materials engineering challenges faced in micromanufacturing. Replacing bulk materials with powdered materials adds a new dimens...

ceutical dosage forms. They serve as carriers for drugs that are topically delivered by way of the skin, cornea, rectal tissue, nasal mucosa, vagina, buccal tissue, urethral membrane, and external ear lining (1). Because of their peculiar rheological behavior, semisolids can adhere to the application surface for sufficiently long periods before they are washed off. This property helps prolong d...