echium amoenum is an iranian indigenous medicinal plant. in this research the effect of hydroalchoholic extract of this plant on sodium-selenite induced cataract formation was evaluated. fifty five white rat pups were selected and divided into six groups. in first group (control 1) no elements injected. second group (control 2) was received normal saline on 11-18 postpartum. hydroalchoholic ext...

Various enzymic systems, such as nitrite reductase, sulfite reductase and glutathione reductase, have been proposed for, or suspected to be involved in, the reduction of selenite in bacteria. As alphaproteobacteria have been shown to be highly tolerant to transition metal oxyanions, it seemed interesting to investigate the hypothetical involvement of these different enzymes in the reduction of ...

The efficiency of strontium selenite and selenite F broths in the isolation of S. typhi from 625 clinical stool specimens were compared. A total of 126 strains of S. typhi were detected. Of these, 96 (76%) were isolated with selenite F broth and 118 (94%) were isolated with strontium selenite broth. At the same time, the number of false positive isolates accruing to strontium selenite broth was...

The concentration of Se in algal cells is a primary determinant of Se tissue contents in higher level consumers. Differences in the ability of algal species to concentrate selenite and variability in ambient selenite concentrations may be important determinants of algal Se contents. We compared uptake of 75Se-labeled selenite by 14 algal species at 2 environmentally relevant selenite concentrat...

• Selenite is a predominant form of selenium (Se) available to plants, especially in anaerobic soils, but the molecular mechanism of selenite uptake by plants is not well understood. • ltn1, a rice mutant previously shown to have increased phosphate (Pi) uptake, was found to exhibit higher selenite uptake than the wild-type in both concentration- and time-dependent selenite uptake assays. Respi...

The aim of this study was to evaluate the radioprotector effect of sodium selenite on the ultrastructure of submandibular glands in rats. Fifty-seven male albino Wistar rats were randomized to 4 groups: control, irradiated, sodium selenite and irradiated/sodium selenite. The animals in the sodium selenite and irradiated/sodium selenite groups received intraperitoneal injections of sodium seleni...

Although the anticancer effects of selenium have been shown in clinical, preclinical, and laboratory studies, the underlying mechanism(s) remains unclear. Our previous study showed that sodium selenite induced LNCaP human prostate cancer cell apoptosis in association with production of reactive oxygen species, alteration of cell redox state, and mitochondrial damage. In the present study, we sh...

The effect of selenite administered at various time intervals after mercury treatment on the toxicity and renal content of mercuric mercury in mice was studied. A marked protective effect of selenite on growth depression and renal lesions caused by mercuric chloride was observed in mice receiving mercury and selenite simultaneously. However, growth depression was not protected by post administr...

Although selenium compounds have been extensively studied as chemopreventative agents for prostate cancer, little is known about the potential use of selenium compounds for chemotherapy. We have shown that selenite inhibits cell growth and induces apoptosis in androgen-dependent LAPC-4 prostate cancer cells. LAPC-4 cells were more sensitive to selenite-induced apoptosis than primary cultures of...

Selenium compounds like selenite and selenate have strong inhibitory effects, particularly on mammalian tumor cell growth by unknown mechanisms. We found that the addition of sodium selenite and sodium selenate inhibited the growth of human 3B6 and BL41 lymphocytes. Selenite was more potent because 10 microM selenite produced a growth inhibitory effect similar to that of 250 microM selenate. Th...