INTRODUCTION Superficial epithelioma with sebaceous differentiation is a rare benign epithelial neoplasm. It usually involves the head, neck or the back of a middle-age person. To the best of our knowledge, two ocular cases have been reported in the literature. CASE PRESENTATION A 46-year-old man of Italian descent, with a known history of testicular seminoma treated by orchiectomy with chemo...

We report a rare case of sebaceous epithelioma(SE) in the external auditory meatus of an 84-year-old woman. The tumor, measuring 1.5 cm in diameter, was hemispherical, yellowish-brown, elastic and hard. It was removed surgically without complications and there has been no recurrence two years postoperatively. The histopathologic findings were characteristic of a sebaceous epithelioma. The contr...

This report describes two cases of sebaceous epithelioma and its immunohistochemical characterization with CK 14, CK18, p63, Ki67 and Bcl-2 immunostaining. Case 1 was a 12-year-old, intact English Cocker spaniel female presenting with multiple skin nodules over one year. Case 2 was a 7-year-old, spayed poodle female with a five-month history of solitary mass. Hematoxylin and eosin (H&E) stainin...

Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous tumor with peculiar histopathologic characteristics [1]. RASD had been described under various synonyms such as superficial epithelioma with sebaceous differentiation, sebocrine adenoma, poroma with sebaceous differentiation, and seborrheic keratosis with sebaceous differentiation [2]. Clinical differential ...

Muir-Torre syndrome (MTS) is a rare inherited cancer syndrome with variable penetrance. MTS follows an autosomal-dominant pattern of inheritance, and is a subtype of Lynch syndrome [formally known as hereditary non-polyposis colorectal cancer (HNPCC)]. MTS is caused by mutations in one of several mismatch repair genes. Patients typically present with sebaceous neoplasms (sebaceous adenoma, seba...

Malherbe and Chenantais were the first to report a pilomatrixoma in 1880. They described a calcifying epithelioma, believing it to be a sebaceous gland tumor. Since 1905, this uncommon neoplasia has been called Malherbe’s calcifying epithelioma. Numerous studies suggest that this tumor stems from the external sheath of hair follicles. In 1961, Forbis and Helwig proposed the term pilomatrixoma, ...

Sebaceomas are uncommon benign dermal lesions [1]. Troy and Ackerman coined the term sebaceoma to describe what was earlier known as sebaceous epithelioma, two decades ago [1,2]. Sebaceoma is a benign sebaceous tumour with >50% basaloid cell content. Sebaceoma is usually not suspected clinically due to its rarity [1]. Clinically, it presents as solitary papule or nodule on the face and scalp af...

Abstract Pilomatricoma, pilomatrixoma, or calcified epithelioma of Malherbe is an uncommon, benign, isolated tumor hair matrix primarily seen in children and young adults. The most common location the head neck region. It usually manifests as a small nodular mass. Here we report rare case giant pilomatricoma over sternum 60-year-old male patient with unusual clinical radiological presentation m...

We report a 62-year-old man with rectal cancer, two keratoacanthomas and multiple sebaceous adenomas, epitheliomas and sebaceous hyperplasia. His brother and father died from colorectal cancer. A subgroup of patients with the Muir-Torre syndrome (MTS) is allelic to the cancer family syndrome. This genetic disorder is caused by an autosomal dominant inherited germline mutation in one of the DNA ...