OBJECTIVE Low-gradient (LG) severe aortic stenosis (AS) and preserved EF with reduced stroke volume are associated with an adverse prognosis, but the relationship of stroke volume index (SVI) with mortality among a range of values is unknown. We investigated the prognostic impact of SVI in this population. METHODS We examined 405 consecutive patients with preserved EF (≥50%) and severe AS (va...

The aim of this study was to compare stroke volume (SVI) to cardiac index (CI) guided resuscitation in a bleeding-resuscitation experiment. Twenty six pigs were randomized and bled in both groups till baseline SVI (T bsl) dropped by 50% (T 0), followed by resuscitation with crystalloid solution until initial SVI or CI was reached (T 4). Similar amount of blood was shed but animals received sign...

Stochastic variational inference (SVI) uses stochastic optimization to scale up Bayesian computation to massive data. We present an alternative perspective on SVI as approximate parallel coordinate ascent. SVI trades-off bias and variance to step close to the unknown true coordinate optimum given by batch variational Bayes (VB). We define a model to automate this process. The model infers the l...

Since systemic sclerosis (SSc) also involves the heart, the aim of the present study was to evaluate possible differences in right ventricular (RV) pump function between SSc-associated pulmonary arterial hypertension (PAH; SScPAH) and idiopathic PAH (IPAH). In 13 limited cutaneous SScPAH and 17 IPAH patients, RV pump function was described using the pump function graph, which relates mean RV pr...

AIMS We aimed to evaluate the prognostic significance of histopathological patterns of seminal vesicle invasion (SVI) after radical prostatectomy. METHODS AND RESULTS Seminal vesicles of 1050 radical prostatectomy specimens from the Karolinska Hospital, from 1998 to 2005, were reviewed. Extraprostatic SVI was found in 60 cases (5.7%). Associations between histopathological characteristics of ...

OBJECTIVE To evaluate the relationships between the changes in stroke volume index (SVI), measured in both the aorta and the pulmonary artery, and the changes in intrathoracic blood volume index (ITBVI), as well as the relationship between changes in aortic SVI and changes in the pulmonary artery wedge pressure (PAWP). DESIGN Prospective study with measurements at predetermined intervals. S...

In this article, we show how to calibrate the widely-used SVI parameterization of the implied volatility smile in such a way as to guarantee the absence of static arbitrage. In particular, we exhibit a large class of arbitrage-free SVI volatility surfaces with a simple closed-form representation. We demonstrate the high quality of typical SVI fits with a numerical example using recent SPX optio...

Many frequent and severe air pollution incidents have emerged across the vast parts of China recently. The identification of factors and mapping social vulnerability has become extremely necessary for environmental management and sustainable development. However, studies associating social vulnerability with air pollution remain sparse. With reference to research achievements of social vulnerab...

AIMS To determine the causes of severe visual impairment and blindness (SVI/BL) in children in Suriname (Dutch Guyana) and to identify preventable and treatable causes. METHODS 4643 children under 16 years of age were recruited from two locations: 33 children attending the only school for the blind were examined and 4610 medical records were analysed at an eye clinic. Data have been collected...