Most software for Multiple Criteria Decision Analysis (MCDA) implement a small set of compatible methods in a closed monolithic software. Sometimes, however, the model can be generated through external information sources and therefore the supporting software should enable their integration. This paper motivates the need for model generation through existing applications of Stochastic Multicrit...

Stochastic multiobjective acceptability analysis (SMAA) is a multicriteria decision support method for multiple decision makers in discrete problems. In SMAA, the decision makers need not express their preferences explicitly or implicitly. Instead, the method is based on exploring the weight space in order to describe the valuations that would make each alternative the preferred one. Inaccurate...

OBJECTIVE Mouse models possessing green fluorescent protein (GFP) and/or human aldose reductase (hAR) in vascular tissues have been established and crossed with naturally diabetic Akita mice to produce new diabetic mouse models. RESEARCH DESIGN AND METHODS Colonies of transgenic C57BL mice expressing GFP (SMAA-GFP), hAR (SMAA-hAR) or both (SMAA-GFP-hAR) in vascular tissues expressing smooth m...

We have previously shown that immunization with solid matrix-antigen-antibody (SMAA) complexes induces both vigorous humoral and cell-mediated immune responses and have suggested that this method of vaccination may be developed for use in humans, and potentially as a vaccine against AIDS. Here we demonstrate that a small oligopeptide can act as a tag for the construction of SMAA complexes using...

We have previously shown that the adoptive transfer of splenocytes, isolated from mice immunized by infection with the paramyxovirus simian virus 5 (SV5), enhance the speed of clearance of SV5 from the lungs of immunodeficient mice; clearance is mediated primarily through CD8+ effector cells and not by serum neutralizing antibody (D.F. Young, R.E. Randall, J.A. Hoyle, and B.E. Souberbielle, J. ...

Stochastic Multicriteria Acceptability Analysis (SMAA) comprises a family of multiple criteria decision aiding (MCDA) methods for problems including incomplete, imprecise, and uncertain information. Methods of the family allow solving MCDA problems of various types. Even though the methods have been applied in the past in various real-life decision-making situations, the structure of a unified ...

We have previously shown that mice immunized with solid-matrix-antibody-antigen (SMAA) complexes in the absence of adjuvants show vigorous humoral and cell-mediated immune responses to the immunizing antigen. Here we report that various proteins involved in inducing protective immune responses to different viruses can easily and simply be incorporated into SMAA complexes and that such complexes...

BACKGROUND Superior mesenteric artery aneurysm (SMAA) is an uncommon vascular disorder. Complications such as rupture have been reported. Once complication has been encountered both surgical and endovascular treatment techniques can be considered. CASE REPORT We present a case of 68-year old male patient with SMAA rupture treated by endovascular modality. CONCLUSIONS Endovascular therapy is...

Stochastic Multicriteria Acceptability Analysis (SMAA) is a family of methods to aid decision makers (DMs) in discrete decision making problems. SMAA methods are capable of handling preference information of various types. The imprecise preferences of multiple DMs can for example be represented by a joint probability distribution for criteria weights. Dempster-Shafer theory with Analytic Hierar...