The TRAP (thyroid hormone receptor associated proteins)/Mediator complex serves as a transcriptional coactivator. In Drosophila, Kohtalo (Kto) and Skuld (Skd), homologs of TRAP subunits, TRAP230 and TRAP240, respectively, are necessary for eye development. However, the transcriptional activators that require Kto and Skd have not been identified. Here we provide evidence that Kto and Skd are ess...

The difference in threshold sensitivities that are found when examining the visual field (VF) with static versus kinetic perimetric methods is called stato-kinetic dissociation (SKD). In this pilot study, we describe a semi-automated procedure for quantifying SKD. Fifteen patients with VF defects were examined with kinetic and static perimetry. SKD values were defined as positive when the stati...

Wire electric discharge machine (WEDM) is spark erosion in unconventional machining technique to cut hard and the conductive material with a wire as an electrode. The blanking die material SKD 11 is a high carbon and high chromium tool steel with high hardness and high wearing resistance property. This tool steel has broad application in press tools and dies making industries. In this research ...

Polusi plastik telah menjadi perhatian global karena pembuangan sampah yang buruk mencemari lingkungan. Pengelolaan limbah plastic secara mandiri dapat dilakukan ditingkat lokal sebagai alternatif upaya daur ulang mandiri. Mesin Shredder sederhana banyak digunakan dengan design mudah, perawatan dan suku cadang tersedia lokal. shredder adalah mesin paling awal untuk memotong potongan-potongan ke...

OBJECTIVE Approximately 10% to 15% of Kawasaki disease (KD) is refractory to treatment with initial intravenous immunoglobulin (IVIG). However, there is no consensus on pharmacologic treatment of refractory KD (rKD). Demographic characteristics of patients with rKD and regional variability in their treatment in the United States have not been reported on a large scale. The goal of this study wa...

Artificial transcription factors (ATFs) and genomic nucleases based on a DNA binding platform consisting of multiple zinc finger domains are currently being developed for clinical applications. However, no genome-wide investigations into their binding specificity have been performed. We have created six-finger ATFs to target two different 18 nt regions of the human SOX2 promoter; each ATF is co...

1Associate Professor and Head,Department of EEE, SKD College of Engineering, Gooty, AP, India 2PG Student, SKD College of Engineering, Gooty, AP, India 3Principal, SKD College of Engineering, Gooty, AP, India ------------------------------------------------------------------------------***------------------------------------------------------------------------------Abstract The objective of thi...