Ligand 2-diphenylphosphinothiophenol (Hsarp) reacted with Pt(PPh3)4 to yield trans-[PtH(sarp)(PPh3)], which undergoes fast exchange with free PPh3 on the NMR time scale and very slowly and reversibly formed some cis-[PtH(sarp)(PPh3)] over time in solution (11%, 24 h). Reaction of trans-[PtH(sarp)(PPh3)] with Hsarp in boiling toluene gave cis- and trans-[Pt(sarp)2]; the cis isomer being more sta...

We describe a networking infrastructure, called wireless open service networks, that allows service providers such as content providers to compete in open marketplaces. Using this open infrastructure, customers are empowered with dynamic choice of a variety of services at various levels, beyond just their traditional choices in network access services. In the meantime, service providers are giv...

BACKGROUND To evaluate the association between the clinical, dosimetric factors and severe acute radiation pneumonitis (SARP) in patients with locally advanced non-small cell lung cancer (LANSCLC) treated with concurrent chemotherapy and intensity-modulated radiotherapy (IMRT). METHODS We analyzed 94 LANSCLC patients treated with concurrent chemotherapy and IMRT between May 2005 and September...

RATIONALE Identification and characterization of asthma phenotypes are challenging due to disease complexity and heterogeneity. The Severe Asthma Research Program (SARP) used unsupervised cluster analysis to define 5 phenotypically distinct asthma clusters that they replicated using 3 variables in a simplified algorithm. We evaluated whether this simplified SARP algorithm could be used in a sep...

Control of polyene macrolide production in Streptomyces natalensis is mediated by the transcriptional activator PimR. This regulator combines an N-terminal domain corresponding to the Streptomyces antibiotic regulatory protein (SARP) family of transcriptional activators with a C-terminal half homologous to guanylate cyclases and large ATP-binding regulators of the LuxR family. The PimR SARP dom...

PP1 (protein phosphatase 1) is a ubiquitously expressed serine/threonine-specific protein phosphatase whose activity towards different substrates appears to be mediated via binding to specific proteins that play critical regulatory and targeting roles. In the present paper we report the cloning and characterization of a new protein, termed SARP (several ankyrin repeat protein), which is shown t...

In this article, we propose a total variation (TV) based model for removing multiplicative Gamma noise. The model integrates the data-fitting energy proposed in [1] with a spatially adaptive regularization parameter (SARP) approach. The data-fidelity term enables to deal with heavy multiplicative noise. And the SARP allows to preserve textures and edges while effectively removing the noise in h...

The flexibility of movement for the wireless ad hoc devices, referred to as node mobility, introduces challenges such as dynamic topological changes, increased frequency of route disconnections and high packet loss rate in Mobile Ad hoc Wireless Network (MANET) routing. This research proposes a novel on-demand routing protocol, Speed-Aware Routing Protocol (SARP) to mitigate the effects of high...

BACKGROUND Oxytetracycline (OTC) is a broad-spectrum antibiotic commercially produced by Streptomyces rimosus. Despite its importance, little is known about the regulation of OTC biosynthesis, which hampered any effort to improve OTC production via engineering regulatory genes. RESULTS A gene encoding a Streptomyces antibiotic regulatory protein (SARP) was discovered immediately adjacent to t...

common and potentially deleterious rare variation in this pathway would be associated with severe asthma based on SARP cluster designation. Methods: To evaluate common variants (minor allele frequency or MAF .5%), 419 SARP non-Hispanic white participants with a cluster assignment were genotyped for 182 single nucleotide polymorphisms (SNPs) in Th2 pathway genes using whole-genome SNP data. Indi...