bluetongue is an infectious disease that primarily affects sheep. but due to serious socioeconomic consequence of it outbreaks on the international trade it has been included in the oie notifiable diseases (list a). during 2007-8, total number of 130 blood samples gathered from suspected sheep to bluetongue disease in seropositive region including khuzestan, kurdistan, fars, ilam and qum provin...

Rice black-streaked dwarf virus (RBSDV) causes maize rough dwarf disease or rice black-streaked dwarf disease and can lead to severe yield losses in maize and rice. To analyse RBSDV evolution, codon usage bias and genetic structure were investigated in 111 maize and rice RBSDV isolates from eight geographic locations in 2013 and 2014. The linear dsRNA S7 is A+U rich, with overall codon usage bi...

Intersubspecific hybrid sterility is a common form of reproductive isolation in rice (Oryza sativa L.), which significantly hampers the utilization of heterosis between indica and japonica varieties. Here, we elucidated the mechanism of S7, which specially causes Aus-japonica/indica hybrid female sterility, through cytological and genetic analysis, map-based cloning, and transformation experime...

Previous phylogenetic analyses based on bluetongue virus (BTV) gene segment L3, which encodes the inner core protein, VP3, indicated a geographical distribution of different genotypes. The inner core protein, VP7, of BTV has been identified as a viral attachment protein for insect cell infection. Because the inner core proteins are involved with infectivity of insect cells, we hypothesized that...

We have resolved B220+ IgM- B-lineage cells in mouse bone marrow into four fractions based on differential cell surface expression of determinants recognized by S7 (leukosialin, CD43), BP-1, and 30F1 (heat stable antigen). Functional differences among these fractions can be correlated with Ig gene rearrangement status. The largest fraction, lacking S7, consists of pre-B cells whereas the others...

  Bluetongue is an infectious disease that primarily affects sheep. But due to serious socioeconomic consequence of it outbreaks on the international trade it has been included in the OIE notifiable diseases (list A). During 2007-8, total number of 130 blood samples gathered from suspected sheep to bluetongue disease in seropositive region including Khuzestan, Kurdistan, Fars, Ilam and Qum prov...

Bacterial ribosomal protein S7 initiates the folding of the 3' major domain of 16S ribosomal RNA by binding to its lower half. The X-ray structure of protein S7 from thermophilic bacteria was recently solved and found to be a modular structure, consisting of an alpha-helical domain with a beta-ribbon extension. To gain further insights into its interaction with rRNA, we cloned the S7 gene from ...

Supporting Figure 1. Kinase inhibitory activity of compound 18 . S2 Supporting Figure 2. Activity of compound 18 in tumor models S3 Synthesis and Characterization of Compounds 7h, 11–17, and 19–24 S4 Biopharmaceutical Profiling S7 Rat Pharmacokinetics S7 Cell Viability Assay S7 Murine P388/D1 Leukemia Model S7 NCI-H460 Xenograft S7 X-Ray Crystallography S8 Molecular Modeling S8 Supplementary Re...

during 1387-86, total number of 120 blood samples gathered from sheep with bluetongue-like clinical sign. the samples collected from seropositive regions .after separating serum, they were evaluated by competitive elisa for detecting ab against vp7 antigen. the full length of s7 gene (1156 bp) amplified by one step rt-pcr .in this method two sets specific primers, targeting 3? and 5?ends of s7 ...