نتایج جستجو برای: S19

تعداد نتایج: 509  

Journal: :Iranian journal of veterinary research 2016
F Mukherjee A Prasad V S Bahekar S K Rana L Rajendra G K Sharma V A Srinivasan

The use of liposome as an adjuvant and a vaccine carrier has been cited previously in the literature. It has also been shown to be effective in enhancing the immunogenicity of vaccine candidates. BALB/c mice immunized subcutaneously with outer membrane protein (OMP) of Brucella abortus S19 vaccine strain entrapped in a commercial cationic liposome (S19-OMP-liposome) for vaccine delivery, showed...

Journal: :Vaccine 2011
Carlos Chacón-Díaz Melissa Muñoz-Rodríguez Elías Barquero-Calvo Caterina Guzmán-Verri Esteban Chaves-Olarte María Jesús Grilló Edgardo Moreno

Brucellosis is an important malady of productive and wildlife animals and a worldwide zoonosis. The use of effective vaccines and the corresponding diagnostic tests that allow differentiating infected from vaccinated animals are essential tools to control the disease. For this, a prototype of Brucella abortus S19 vaccine expressing green fluorescent protein (S19-GFP) was constructed. The S19-GF...

2012
Hiroshi Nishiura Rui Zhao Tetsuro Yamamoto

The transcriptional nuclear factor binding to the Y box of human leukocyte antigen genes (NF-Y) for the C5a receptor (C5aR) gene is active in erythroblasts. However, the roles of the C5aR in erythropoiesis are unclear. We have previously demonstrated that apoptotic cell-derived ribosomal protein S19 (RP S19) oligomers exhibit extraribosomal functions in promoting monocyte chemotaxis and proapop...

Journal: :Haematologica 2014
Pekka Jaako Shubhranshu Debnath Karin Olsson Ute Modlich Michael Rothe Axel Schambach Johan Flygare Stefan Karlsson

Diamond-Blackfan anemia is a congenital erythroid hypoplasia caused by functional haploinsufficiency of genes encoding ribosomal proteins. Mutations involving the ribosomal protein S19 gene are detected in 25% of patients. Enforced expression of ribosomal protein S19 improves the overall proliferative capacity, erythroid colony-forming potential and erythroid differentiation of hematopoietic pr...

Journal: :Infection and immunity 1975
C F Schachtele G R Germaine S K Harlander

A mutant (S19) of Sreptococcus mutans strain 6715 which produces elevated levels of dextransucrase (EC 2.4.1.5) was isolated. Soluble enzyme in culture supernatant solutions from S19 polymerized the glucosyl moiety of sucrose into alcohol-insoluble and water-insoluble glucans at a rate three to six times greater than that of the parent strain. Washed-cell suspensions of S19 also contained incre...

Journal: :Clinical and vaccine immunology : CVI 2006
S C Olsen S J Fach M V Palmer R E Sacco W C Stoffregen W R Waters

Previous studies have suggested that currently available brucellosis vaccines induce poor or no protection in elk (Cervus elaphus nelsoni). In this study, we characterized the immunologic responses of elk after initial or booster vaccination with Brucella abortus strains RB51 (SRB51) and 19 (S19). Elk were vaccinated with saline or 10(10) CFU of SRB51 or S19 (n=seven animals/treatment) and boos...

Journal: :Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 2011

2017
Woo Hyeon Jeong Dong Hyun Song Gyeung Haeng Hur Seong Tae Jeong

Four mutations (N23A, Y90A, R110A and F177A) were introduced into S19, a vaccine candidate for staphylococcal enterotoxin B (SEB), resulting in a lower binding affinity towards the T-cell receptor beta chain (TCB) and reducing its superantigen activity. The structure of S19 was solved and was superposed on the native or complex structure of SEB. In the superposition model, mutations that were i...

2016
Hiroshi Nishiura Toru Kawakami Mutsuki Kawabe Nahoko Kato-Kogoe Naoko Yamada Keiji Nakasho Koji Yamanegi

We have demonstrated that ribosomal protein S19 (RP S19) polymer, when crosslinked between Lys122 and Gln137 by activated coagulation factor XIII, acts as a C5a receptor (C5aR) antagonist/agonist. Based on experimental data obtained using RP S19 analog peptide and recombinant protein monomer, we suggested that L131DR, I134AGQVAAAN and K143KH moieties in the RP S19 C-terminus act in, respectivel...

2017
Mohita Sharma Dongshan An Tao Liu Tijan Pinnock Frank Cheng Gerrit Voordouw

Coiled tubing corrosion was investigated for 16 field water samples (S5 to S20) from a Canadian shale gas field. Weight loss corrosion rates of carbon steel beads incubated with these field water samples averaged 0.2 mm/yr, but injection water sample S19 had 1.25±0.07 mm/yr. S19 had a most probable number of zero acid-producing bacteria and incubation of S19 with carbon steel beads or coupons d...

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