Rotaviruses are the most common cause of severe diarrhea in children under 5 years of age worldwide with a higher prevalence in developing countries. In accordance with the World Health Organization (WHO) recommendations for the global use of rotavirus vaccines, it is important to review trends of rotavirus epidemiology, distribution and diversity of rotavirus strains in the pre-vaccine period....

Background and Aims: In humans the group A rotaviruses are associated with endemic diarrhea in children under the age of 5, leading to approximately 800,000 deaths every year. Introduction of rotavirus vaccines into childhood immunization programs can contribute to substantial reduction in mortality from rotavirus gastroenteritis in developing countries and virtually eliminating hospitalization...

the purpose of this study was to evaluate the changes in the serum concentrations of haptoglobin (hp), serum amyloid a (saa) and igg, iga in calves with diarrhea caused by rotavirus, coronavirus, escherichia coli f5 and eimeria species. the experiment was carried out on 40 diarrhoeic and 10 non-diarrhoeic calves (group c). a total of 13 calves were infected with rotavirus or coronavirus (group ...

The purpose of this study was to evaluate the changes in the serum concentrations of haptoglobin (Hp), serum amyloid A (SAA) and IgG, IgA in calves with diarrhea caused by rotavirus, coronavirus, Escherichia coli F5 and Eimeria species. The experiment was carried out on 40 diarrhoeic and 10 non-diarrhoeic calves (group C). A total of 13 calves were infected with rotavirus or coronavirus (group ...

background: the recent studies show that rotavirus is important cause of the acute gastroenteritis. the aim of this review is to estimate the number of rotavirus infection among iranian children by performing a systematic review and estimating a pooled data. methods: we performed a systematic literature review in relevant databases including pubmed, medline, ovid, sid, magiran, and iranmedex. s...

objective: group a rotaviruses (garv) are responsible for the vast majority of severe diarrhea worldwide that kills an estimated 600,000-870,000 children annually. since infantile gastroenteritis is a main health problem, therefore diagnosis and treatment of this disease is crucial. gene rearrangements have been detected in vitro during serial passages of the virus at a high multiplicity of inf...

human rotavirus is a major etiologic agent for infantile diarrhea worldwide. it is responsible for up to 3.3 million deaths per year in children in developing countries. various rapid and sensitive techniques have been developed to readily diagnose rotavirus gastroenteritis. in the present study, we compared the sensitivity and specificity of immunochromatography and rna-polyacrylamide-gel elec...

BACKGROUND Efficacy of live oral rotavirus vaccines is reduced in low-income compared with high-income settings. Parenteral non-replicating rotavirus vaccines might offer benefits over oral vaccines. We assessed the safety and immunogenicity of the P2-VP8-P[8] subunit rotavirus vaccine at different doses in South African toddlers and infants. METHODS This double-blind, randomised, placebo-con...

rotavirus infections are one of the etiological agents of infantile and children,s gastroenteritis.in this study 450 fecal samples from children under 2 years old from cities of Tehran nad Zahedan were collected.of these specimens.73 samples which were cosidered as moderately positive(++) by ELISA were selected.SDS-PAGE analysis showed fifty six different rotavirus electrophoretypes from which ...