in this paper a new isolating system is introduced for short to mid-rise buildings. in comparison to conventional systems such as lrb and hrb, the proposed system has the advantage of no need to cutting edge technology and has low manufacturing cost. this system is made up of two orthogonal pairs of pillow-shaped rollers that are located between flat bed and plates. by using this system in two ...

rolling-based seismic isolation systems, in which rollers of circular or non-circular section are used, are less expensive and easier to manufacture. however, this type of isolation suffers from either lack of restoring or re-centering capability, or weakness against uplift forces. to resolve the first shortcoming the use of elliptical as well as pillow-shape rolling parts has been suggested, a...

Rolling-based seismic isolation systems, in which rollers of circular or non-circular section are used, are less expensive and easier to manufacture. However, this type of isolation suffers from either lack of restoring or re-centering capability, or weakness against uplift forces. To resolve the first shortcoming the use of elliptical as well as pillow-shape rolling parts has been suggested, a...

The present paper aims to demonstrate why usually when theoretical mathematical models are used to compute the frequencies corresponding to a faulty rolling bearing a deviation is obtained between the computed values and the real frequencies emitted by such a device. A laboratory rolling bearing test ring has been developed to perform the current studies. From the obtained results we highlight ...

To study rolling of mouse neutrophils on P- and E-selectins in whole blood and without cell isolation, we constructed an autoperfused flow chamber made from rectangular microslides (0.2x2 mm) perfused from a carotid artery catheter. A differential pressure transducer served to measure wall shear stress. Green fluorescent neutrophils rolled on P-selectin but not E-selectin coated at 50 ng/ml, wi...

A series of large-scale experimental tests is conducted on a mass equipped with a hybrid controlled base-isolation system that consists of rolling pendulum system (RPS) and a 20 kN magnetorheological (MR) damper. The 12-ton mass and its hybrid isolation system are subjected to various intensities of nearand far-fault earthquakes on a large shake table. Fuzzy controllers use feedback from displa...

Advanced management of dysmetabolic syndromes such as diabetes will benefit from a timely mechanistic insight enabling personalized medicine approaches. Herein, we present a rapid microfluidic neutrophil sorting and functional phenotyping strategy for type 2 diabetes mellitus (T2DM) patients using small blood volumes (fingerprick ~100 μL). The developed inertial microfluidics technology enables...

high levels of regulated oncogen-alpha (gro-a) expression have been observed in the liver. gro-a stimulates proliferation of epithelial cells and induction of rolling and extravascular migration of neutrophils and mononuclear cells. given the above observations, this chemokine was chosen to be analyzed in freshly isolated and cultured hepatocytes. in this study, hepatocytes (2×106 cell/ml) were...

Leukocyte rolling is an important step for the successful recruitment of leukocytes from blood to tissues mediated by a specialized group of glycoproteins termed selectins. Because of the dynamic process of leukocyte rolling, binding of selectins to their respective counter-receptors (selectin ligands) needs to fulfill three major requirements: (1) rapid bond formation, (2) high tensile strengt...

The isolation of hematopoietic stem and progenitor cells (HSPCs) is critical for transplantation therapy and HSPC research, however current isolation techniques can be prohibitively expensive, time-consuming, and produce variable results. Selectin-coated microtubes have shown promise in rapidly isolating HSPCs from human bone marrow, but further purification of HSPCs remains a challenge. Herein...