Introduction: The Thiamine Transporter gene SLC19A2 is the only gene known to be associated with TRMA.  This syndrome is a trial clinical characterized by megaloblastic anemia, nonautoimmune diabetes mellitus and sensory-neural hearing loss. Methods: Described here are three children from consanguineous Iranian families with thiamine – responsive megaloblastic anemia (TRMA) or Rogers' syndrome....

Recently, a deletion of chromosome 4pter was found in three patients with Pitt-Rogers-Danks syndrome. We investigated two of these patients, by means of DNA and FISH studies, together with two additional patients with Pitt-Rogers-Danks syndrome, to determine the critical region of the deletion in these patients and to compare this with the critical region in Wolf-Hirschhorn syndrome. All four p...

Received 24 October 1996 Revised version accepted for publication 30 January 1997 Abstract Recently, a deletion of chromosome 4pter was found in three patients with PittRogers-Danks syndrome. We investigated two of these patients, by means of DNA and FISH studies, together with two additional patients with Pitt-Rogers-Danks syndrome, to determine the critical region of the deletion in these pat...

OBJECTIVES This cross-sectional study was performed in order to elucidate the relationship of musculoskeletal complaints with age, gender and physically demanding work in the Netherlands. METHODS Questionnaire data of male (n = 36756) and female (n = 7730) employees, gathered as part of periodical occupational health surveys among active workers in the Netherlands, were stratified for age, ge...

This report describes a female child with thiamine responsive megaloblastic anemia syndrome (Rogers syndrome), presenting with anemia and diabetes mellitus responding to thiamine. She also had retinitis pigmentosa. The anemia improved and blood sugar was controlled with daily oral thiamine. Previously unreported olfactory abnormalities, as described in Wolfram syndrome, were also present in our...

This article reviews the impact of Carl Rogers' postulate about the necessary and sufficient conditions of therapeutic change on the field of psychotherapy. It is proposed that his article (see record 2007-14630-002) made an impact in two ways; first, by acting as a spur to researchers to identify the active ingredients of therapeutic change; and, second, by providing guidelines for therapeutic...

We describe 2 patients with a combination of findings strikingly similar to those described by Pitt et al. [1984], consisting of severe mental retardation, pre- and postnatal growth retardation, history of seizures, microcephaly, ocular proptosis, mid-face hypoplasia, short and flat philtrum, and wide mouth. Our cases included, a total of only 9 patients has been described. One of our patients ...

sprue (Chaudhuri and Rai Chaudhuri, 1944), nutritional diarrhoea (Karamchandani, 1944), incomplete sprue (Manson-Bahr, 1940), chronic jejuno-ileal insufficiency (Bennett and Hardwick, 1940), and vitamin B deficiency syndrome allied to sprue (Cook, 1944). Rogers (Rogers and Megaw, 1942) is of the view that unexplained diarrhoea of more than 10 days' duration should be treated as sprue, provided ...

A technique by Rogers-Ramachandran and Ramachandran [Vis. Res. 38 (1998) 71-77] was adapted to evaluate magnocellular (M) and parvocellular (P) visual processing efficiency, with identical task structure, in normal and dyslexic children. A battery of phonological, orthographic and cognitive tasks was administered to assess reading ability and component reading skills in both groups. For the vis...

Combination of solutionsby Gerry Leversha, St. Paul's School, London, England, and Kenneth M. Wilke, Topeka, KS, USA. Let n, b and c be the sides of the triangle. Since the perimeter n+ b+ c = 4n, if b < n then c > 2n, contradicting the triangle inequality. Hence we can take n < b < c < 2n. Furthermore we can assume that n, b and c are coprime; for, if (n; b) = d > 1 say, then djc since c = 3n ...