نتایج جستجو برای: Rheumatoid Factor
تعداد نتایج: 891751 فیلتر نتایج به سال:
background: single-nucleotide polymorphism (snp) rs2476601 within protein tyrosine phosphatase non-receptor type 22 gene (ptpn22) has been shown to be a risk factor for different autoimmune diseases. this study explored the association of 1858 c/t snp with rheumatoid arthritis (ra) and celiac disease (cd) in a region covering south-west of iran. methods: totally, 52 patients with cd, 120 patien...
objective: anti-cyclic citrullinated peptide (anti-ccp) antibodies are highly specific markers for rheumatoid arthritis (ra) and useful for predicting rheumatoid arthritis (ra) development and progression. we assessed the diagnostic value of anti-ccp antibodies in our patients with ra. materials and methods: anti-ccp antibodies and rheumatoid factor (rf) titers were determined in 247 serum sam...
rheumatoid factors (rf) are autoantibodies with specificity for the fc portion of human igg. production of rf is a characteristic feature of rheumatoid arthritis (ra) and is detectable in high titer in about 90% of these patients. in this study, we measured total igm, iga, igmrf and igarf in serum and synovial fluid of 45 ra patients by elisa and the results were compared with those obtained by...
high levels of rheumatoid factors (rf) are detectable in serum of the majority of patients with rheumatoid arthritis (ra), but 5-10% of patients remain seronegative (sn). despite clinical and genetic similarities between these two subsets of ra, it has been proposed that they may be regarded as distinct clinical entities. methods: in the present study a panel of monoclonal antibodies (mab) reco...
total igm, iga, and igm-rheumatoid factor (rf) and iga-rf were quantitated in the serum and synovial fluid of 35 seropositive and 8 seronegative rheumatoid arthritis (ra) patients, using a sensitive enzyme-linked immunosorbent assay (elisa). mononuclear cells isolated from peripheral blood and synovial fluid of three seropositive patients were also stimulated in vitro with phorbol myristate ace...
in this study we determined the frequency, sensitivity and specificity of anti cyclic citrullinated peptides (anti-ccp) igg antibody, total rheumatoid factor (rf-t), and rf isotypes in iranian patients with rheumatoid arthritis (ra) and their association with age, clinical and serological parameters. anti-ccp and rf-t and rf isotypes level were measured in 418 patients and 399 healt...
a number of patients with inflammatory arthritis due to inadequate clinical or laboratory data do not fulfill diagnostic criteria for a clinical disease categories. these patients with initial diagnosis of undifferentiated arthritis (ua) may remit or progress to a definite well- defined condition such as rheumatoid arthritis (ra) or remain as ua with persistence of inflammatory arthritis. the m...
background: immunopathological and inflammatory processes play important roles in the initiation and development of ischemic heart disease (ihd). objective: the aim of this study was to evaluate the serum levels of several autoantibodies including rheumatoid factor (rf), anti-nuclear antibodies (ana), anti-small nuclear ribonucleoprotein (anti-sm), anti-phosphatidylserine (anti-ps) and anti-car...
Background and Aim: Rheumatoid arthritis is a systemic, chronic and inflammatory disease. It is characterized by the symmetric synovitis of the articules of the extremities. Its major cause is unknown.Immunological factors including Rheumatoid factor (RF) are considered as more confirming Cause. To date Rheumatoid factor is consisted of many antibodies which are produced against the constant r...
Background: There are several evidences that genetic factors besides environmental triggers have important role in initiating the rheumatoid arthritis (RA). The aim of this study was to investigate the association of rheumatoid arthritis with different subtypes of HLA DR4 in Iranian patients. Methods: In an un-matched case control study, 110 rheumatoid arthritis patients (case) and 56 knee ost...
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