OBJECTIVES Chromosome 9p21 single nucleotide polymorphism (SNP) is a susceptibility variant for acute myocardial infarction (AMI) in the primary prevention setting. However, it is controversial whether this SNP is also associated with recurrent myocardial infarction (ReMI) in the secondary prevention setting. The purpose of this study is to evaluate the impact of chromosome 9p21 SNP on ReMI in ...

INTRODUCTION Cardiopulmonary bypass (CPB) can cause stress response that increases levels of cytokine and catecholamine in plasma, resulting in hyperglycemia. In adults, it has been demonstrated that remifentanil infusion during CPB could prevent increases of cytokine, catecholamine, and blood glucose levels, but such effects of remifentanil in children have not been elucidated. AIM In this s...

Biomarker-targeted surface-enhanced Raman scattering (SERS) nanoparticles (NPs) have been explored as a viable option for targeting and imaging multiple cell-surface protein biomarkers of cancer. While it has been demonstrated that this Raman-encoded molecular imaging (REMI) technology may potentially be used to guide tumor-resection procedures, the REMI strategy would benefit from further impr...

As part of a metazoan parasite survey of elasmobranchs from Malaysian Borneo, specimens of Rhoptrobothrium Shipley et Hornell, 1906 were collected from the eagle rays Aetomylaeus maculatus (Gray) and Aetomylaeus niehofii (Bloch et Schneider). The type species is redescribed from its type host, and a neotype specimen is designated. In addition, three new species of Rhoptrobothrium are described:...

Systemic administration of mu-opioids at clinical doses for analgesia typically slows respiratory rate. Mu-opioid receptors (MORs) on pre-Bötzinger Complex (pre-BötC) respiratory neurons, the putative kernel of respiratory rhythmogenesis, are potential targets. The purpose of this study was to determine the contribution of pre-BötC MORs to the bradypnea produced in vivo by intravenous administr...

BACKGROUND Although measurement of cerebral hypnotic drug effect and muscle relaxation is common clinical routine during anaesthesia, a reliable measurement of the neurophysiological effects evoked by a painful stimulus is still missing. Recently, the surgical stress index (SSI) has been introduced as a surrogate measure of 'nociception'. The present study aimed to examine the influence of incr...

The filamentous fungus Monascus pilosus was genetically transformed with a reporter plasmid, pMS-1.5hp, by aurintricarboxylic acid (ATA) treatment to obtain an efficient red-pigment producing mutant. The transformation efficiency of Monascus pilosus was higher with the ATA-treatment than with either a non-restriction-enzyme-mediated integration (REMI) or a REMI method. This valid and convenient...

The COLTRIMS Reaction Microscope C-REMI can image the momentum vectors of all emitted charged fragments in an atomic or molecular reactions similar to bubble chamber high energy particle physics. detect with “zero” kinetic ultrahigh vacuum environment by projecting them weak electromagnetic fields onto position-sensitive detectors. Geometrically a nearly 4π collection solid angle and 50% effici...

geological conditions of tabriz, a growing city in nw-iran, are strongly influenced by north tabriz fault (ntf). north tabriz fault is a major seismogenic fault in nw-iran. so, for a correct seismic microzonation, shear wave velocity (vs) structure in different part of city should be determined. but urban conditions, such as ambient noise due to cultural activity, restrict the general applicati...