OBJECTIVE To compare the effectiveness of an electrocautery strategy with ovulation induction using recombinant follicle stimulating hormone in patients with polycystic ovary syndrome. DESIGN Randomised controlled trial. SETTING Secondary and tertiary hospitals in the Netherlands. PARTICIPANTS 168 patients with clomiphene citrate resistant polycystic ovary syndrome: 83 were allocated elec...

OBJECTIVE This study evaluated the use of Corifollitropin alfa in patients with previous poor response to recombinant follicle stimulating hormone in long-term protocols using gonadotropin-releasing hormone. METHODS Twenty-seven poor responders to previous treatment with the long term protocol using the recombinant follicle stimulating hormone (Group 1) were selected and then submitted to a s...

BACKGROUND The purpose of this study was to compare Gonal-F(®), a recombinant follicle-stimulating hormone, with Menopur(®), a highly purified human menopausal gonadotrophin (hpHMG) in assisted reproduction in Greece. METHODS A decision tree in combination with a Markov model was used to assess the clinical and economical impact of comparators for up to three consecutive cycles. Transition pr...

Background The aim of this study was to evaluate the efficacy and safety of a recombinant human follicle stimulating hormone (r-FSH) low-dose step-up regimen for controlled ovarian hyperstimulation in patients undergoing ovulation induction (OI) with intrauterine insemination (IUI). MaterialsAndMethods The study was conducted in the Department of Obstetrics and Gynecology, Far Eastern Memorial ...

background: the aim of this study was to evaluate the efficacy and safety of a recombinant human follicle stimulating hormone (r-fsh) low-dose step-up regimen for controlled ovarian hyperstimulation in patients undergoing ovulation induction (oi) with intrauterine insemination (iui). materials and methods: the study was conducted in the department of obstetrics and gynecology, far eastern memor...

Background: Leukemia inhibitory factor (LIF) is a pleiotropic cytokine of interleukin-6 family with a remarkable range of biological actions such as proliferative effects on the granulosa and theca cells. The aim of this study was to evaluate the effects of LIF on the growth and maturation of mouse fresh and vitrified preantral follicles, an in vitro model was developed. Methods: The ovaries of...

Background: Follicle stimulating hormone is a heterodimeric protein composed of two subunits, α and ß, which are linked noncovalently. The hypophysial gonadotropin FSH plays an important role in the regulation of oocyte maturation, and a key component for growth of ovulator follicles in ewes. Materials and Methods: This study seeks to clone and express the ovine follicle stimulating hormone sub...

BACKGROUND Gonadotropins are protein hormones which are central to the complex endocrine system that regulates normal growth, sexual development, and reproductive function. There is still a lively debate on which type of gonadotropin medication should be used, either human menopausal gonadotropin or recombinant follicle-stimulating hormone. The objective of the study was to perform a systematic...

background: leukemia inhibitory factor (lif) is a pleiotropic cytokine of interleukin-6 family with a remarkable range of biological actions such as proliferative effects on the granulosa and theca cells. the aim of this study was to evaluate the effects of lif on the growth and maturation of mouse fresh and vitrified preantral follicles, an in vitro model was developed. methods: the ovaries of...