methyl tertiary-butyl ether (mtbe) is used to reduce carbon monoxide and ozone in urban air and to boost fuel octane. there is a lack of knowledge in the literature about the histomorphometric changes of the testis following exposure to mtbe. therefore, this experimental study was performed to determine the effect of oral exposure to mtbe on histologic and histomorphometric changes of testis in...

introduction: anabolic – androgenic steroids (aas) are used at high doses by athletes for improving athletic ability, muscle mass and physical appearance. unfortunately, the abuse of these agents has been significantly increased. it has been established that exercise and high doses of aas may influence the hypothalamic-pituitary-gonadal axis, which can in turn affect testicular apoptosis and ma...

background: previous researches about the effects of epididymal obstruction on the testes are contradictory, and the mechanism harmful effect of male duct system obstruction on seminiferous tubules still remains unclear. objective: the aim of this study was to investigate the effects of epididymal obstruction in prepubertal rats on the testis. materials and methods: 15 days of age, the young ra...

background: ciprofloxacin is a commonly prescribed antibiotic in the treatment of genitourinary tract infection. objective: the aim of this study was to investigate the effects of ciprofloxacin on testis apoptosis and sperm parameters in rat. materials and methods: twenty male wistar rats were selected and randomly divided into two groups; control (n=10) and experimental (n=10). the experimenta...

background: acyclovir (acv), a synthetic purine nucleoside analogue, is known to be toxic to gonads. objective: the current study evaluated cytotoxicity of acv on histopathological changes in testis tissue and serum testosterone and lipid peroxidation concentrations of male rats. materials and methods: animals were divided into five groups. one group served as control and one group served as co...

background: bleomycin (bl) is a glycopeptide antibiotic obtained from the bacterium streptomyces verticillus which is routinely used for treatment of human cancers. royal jelly (rj) is a production from the hypo pharyngeal, mandibular and post cerebral glands of nurse bees. rj consists of 66% water, 15% sugars, 5% lipids, and 13% proteins, essential amino acids and vitamins. objective: the aim ...

this study investigates the effects of melatonin on the sperm quality and testis weight after the combination of swimming exercise and nandrolone decanoate (deca). two groups of male wistar rats were treated for eight weeks as follows; group a consist of co (control), sham, n (deca), s (swimming) and ns (deca plus swimming); and group b: sham m (sham melatonin), m (melatonin), mn (melatonin plu...

background:in recent years, the use of chemicals in agriculture, industry, and public health has become so common that the environment is continuously contaminated by the toxic substance-like metals. aluminum released due to anthropogenic activities such as mining and industrial uses. aluminium has several industrial uses. the present study was designed to investigate the effect of aluminium ch...

background: most studies on anabolic-androgenic steroids abuse have been done in adult rats, but few data are available to immature. objective: this study was conducted to assay the effect of nandrolone decanoate (nd) on the testis and testosterone concentration in male immature rats compare with mature ones in short and long time. materials and methods: 40 mature rats were divided into 4 group...

background: ginger rhizome (zingiber officinale r., family: zingiberaceae) is used medicinally and as a culinary spice. objective: medicinal use of ginger dates back to ancient china and india. ginger and its constituents are stated to have antiemetic, antithrombotic, antihepatotoxic, anti-inflammatory, stimulant, cholagogue and antioxidant. it has been used since ancient time as medicinal and ...