نتایج جستجو برای: Radiosensitivity

تعداد نتایج: 3339  

Journal: :international journal of molecular and cellular medicine 0
farideh elahimanesh cellular & molecular biology research center (cmbrc), babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) ali shabestani monfared cellular & molecular biology research center (cmbrc), babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) meysam khosravi farsani cellular & molecular biology research center (cmbrc), babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) haleh akhavan niaki cellular & molecular biology research center (cmbrc), babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) zeinab abedian cellular & molecular biology research center (cmbrc), babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) karimollah hajian-tilaki cellular & molecular biology research center (cmbrc), babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences)

many biological factors affect radiosensitivity. in this study, radiosensitivity among the different blood groups was investigated. peripheral blood sample of 95 healthy people were divided into two parts. one part was irradiated with 2 gy co-60 gamma rays and the second one was considered as control. then all the samples were studied by cytokinesis-blocked micronucleus assay (cbmn assay). our ...

Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our ...

Journal: :iranian journal of radiation research 0
h. mozdarani department of medical genetics, faculty of medical sciences, tarbiat modares university, tehran, iran a.h. ziaee mashhadi department of radiology technology, faculty of para-medical sciences, mashhad university of medical sciences, mashhad, iran z. alimohammadi department of genetics, science and research branch, islamic azad university, tehran, iran

background: chromosomal alterations play an important role in carcinogenesis. enhanced chromosomal radiosensitivity is shown for many cancer predisposition conditions including breast cancer. in this study chromosomal radiosensitivity and the frequency of background sister chromnatid exchanges (sce) in lymphocytes of normal individuals and breast cancer patients was compared. materials and meth...

Journal: :basic and clinical cancer research 0
asghar ramyar department of hematology and oncology of children’s medical center, tehran university of medical sciences, tehran, iran asghar aghamohammadi research center for immunodeficiencies, pediatrics center of excellence, children’s medical center, tehran university ofmedical sciences, tehran, iran hossein mozdarani department of medical genetics, school of medical sciences, tarbiat modares university, tehran, iran majid mahmoodi cancer research center, tehran university of medical sciences, tehran, iran cyrus azimi genetics group, cancer research center, cancer institute,tehran university of medical sciences, tehran, iran zahra safari cancer research center, tehran university of medical sciences, tehran, iran

background: acute lymphoblastic leukemia (all) constitutes a heterogeneous group of diseases characterized by abnormal proliferation and accumulation of immature lymphoblasts arrested at various differentiation stages. increasing evidence suggests that chromosomal defects are present in these patients. the aim of this study is to investigate the chromosomal radiosensitivity in a group of all pa...

A.H. Ziaee Mashhadi, H. Mozdarani, Z. Alimohammadi,

Background: Chromosomal alterations play an important role in carcinogenesis. Enhanced chromosomal radiosensitivity is shown for many cancer predisposition conditions including breast cancer. In this study chromosomal radiosensitivity and the frequency of background sister chromnatid exchanges (SCE) in lymphocytes of normal individuals and breast cancer patients was compared. Materials...

H. Mozdarani, M. Salimi, N. Bakhtari,

About 10% of apparently normal individuals are sensitive to clastogenic effects of physico-chemical agents. More than 45% of breast cancer patients’ exhibit elevated radiosensitivity. Although the nature of inherent radiosensitivity is not fully understood, but insufficiency and impaired DNA repair mechanism might be prime cause of radiosensitivity. This is evident from genetically affect...

Journal: :International Journal of Human Genetics 2022

The researchers aimed to evaluate the effects of long non-coding ribonucleic acid plasmacytoma variant translocation 1 (lncRNA PVT1) regulating octamer binding transcription factor 4 (OCT4) expression on hepatocellular carcinoma (HCC) cells. It was discovered that in contrast blank group, si-PVT1 group had lower PVT1 and OCT4 expressions, number invading cells wound healing rate, higher radiose...

2013
Farideh Elahimanesh Ali Shabestani Monfared Meysam Khosravifarsani Haleh Akhavan Niaki Zeinab Abedian Karimollah Hajian-Tilaki Sajad Borzouisileh Nayer Seyfizadeh Mehrangiz Amiri

Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1985
R Parshad K K Sanford G M Jones

We reported previously that human cells after neoplastic transformation in culture had acquired an increased susceptibility to chromatid damage induced by x-irradiation during the G2 phase of the cell cycle. Evidence suggested that this results from deficient DNA repair during G2 phase. Cells derived from human tumors also showed enhanced G2-phase chromosomal radiosensitivity. Furthermore, skin...

Hosein Azimian, Mahdieh Dayyani Mahmoud Mahmoudi Mohammad Taghi Bahreyni Toossi,

Introduction: To enhance radiation therapy efficiency it is crucial to implement an individual-based treatment. The aim of present study was to identify the mechanism of intrinsic apoptosis pathway on radiosensitivity and normal tissue complications caused by the radiotherapy.   Materials and Methods: radiation-induced apoptosis in periphera...

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