نتایج جستجو برای: RON
تعداد نتایج: 2469 فیلتر نتایج به سال:
هدف: ارایه نتایج حاصل از 4 روش درمانی مختلف در بیماری انسداد سیاهرگ مرکزی شبکیه (CRVO) از نظر بهترین دید اصلاح‌شده (BCVA) در مقایسه با سیر طبیعی بیماری. روش پژوهش: این مطالعه بر روی 63 چشم از 63 بیمار در 5 گروه به شرح زیر انجام شد: 13 چشم در گروه نوروتومی شعاعی عصب بینایی (RON: radial optic neurotomy)، 10 چشم در گروه ترکیب RON و تزریق داخل چشمی تریامسینولون (IOT: intraocular triamcinolone)،...
purpose: to compare the visual outcomes of four different therapeutic modalities for central retinal vein occlusion (crvo) with each other and with the natural course of the disease. methods: this study was conducted on 63 eyes of 63 patients including 13 eyes in the radial optic neurotomy (ron) group, 10 eyes in the combined ron and intraocular triamcinolone injection (ron/ iot) group, 12 eyes...
purpose: to evaluate the efficacy of radial optic neurotomy (ron) combined with or without intravitreal triamcinolone acetonid (ivta) injection in the management of central retinal vein occlusion (crvo). methods: this non-randomized clinical trial was conducted on 23 patients with crvo, who underwent ron with or without ivta injection. preoperative and postoperative best corrected visual acuity...
The RON tyrosine kinase receptor is under investigation as a novel target in pancreatic cancer. While RON mutations are uncommon, RON isoforms are produced in cancer cells via a variety of mechanisms. In this study we sought to: 1) characterize RON isoform expression in pancreatic cancer, 2) investigate mechanisms that regulate isoform expression, and 3) determine how various isoforms effect ge...
I would like to begin by thanking Ron Chrisley for his interesting and detailed commentary.1 There is much I find to agree with; indeed, it seems to me that his essay can largely be read, not as a criticism of the perspective offered in my own article,2 but rather as a useful and largely complementary alternate view. I am especially grateful for the insights expressed in the last section of the...
Human RON (Recepteur d'Origine Nantais) receptor tyrosine kinase is a cell surface receptor for Macrophage Stimulating Protein (MSP). RON mediates signal transduction pathways that regulate cell adhesion, invasion, motility and apoptosis processes. Elevated levels of RON and its alternatively spliced variants are implicated in the progression and metastasis of tumor cells. The binding of MSP α/...
The proto-oncogene recepteur d'origine nantais (RON, MST1R) and its alternatively spliced variants are involved in various tumor biological processes, such as cell motility, adhesion, proliferation, apoptosis and epithelial-to-mesenchymal transition (EMT). RON overexpression and the occurrence of specific alternatively spliced RON isoforms have been detected in ovarian cancer. In the present st...
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