نتایج جستجو برای: RDS

تعداد نتایج: 2405  

Journal: :The Journal of biological chemistry 2015
Michael W Stuck Shannon M Conley Muna I Naash

The photoreceptor-specific glycoprotein retinal degeneration slow (RDS, also called PRPH2) is necessary for the formation of rod and cone outer segments. Mutations in RDS cause rod and cone-dominant retinal disease, and it is well established that both cell types have different requirements for RDS. However, the molecular mechanisms for this difference remain unclear. Although RDS glycosylation...

Journal: :Human molecular genetics 2009
Dibyendu Chakraborty Xi-Qin Ding Shannon M Conley Steven J Fliesler Muna I Naash

It is commonly assumed that the ultrastructural organization of the rim region of outer segment (OS) discs in rods and lamellae in cones requires functional retinal degeneration slow/rod outer segment membrane protein 1 (Rds/Rom-1) complexes. Cysteine-150 (C150) in Rds has been implicated in intermolecular disulfide bonding essential for functional Rds complexes. Transgenic mice containing the ...

Journal: :Social Networks 2013
Xin Lu

Respondent-driven sampling (RDS) is currently widely used for the study of HIV/AIDS-related high risk populations. However, recent studies have shown that traditional RDS methods are likely to generate large variances and may be severely biased since the assumptions behind RDS are seldom fully met in real life. To improve estimation in RDS studies, we propose a new method to generate estimates ...

Journal: :Journal of applied physiology 2005
Frank van Bel Vincent Latour Hendrik J Vreman Ronald J Wong David K Stevenson Paul Steendijk Johannes Egberts Tannette G Krediet

Infant respiratory distress syndrome (RDS) involves inflammatory processes, causing an increased expression of inducible heme oxygenase with subsequent production of carbon monoxide (CO). We hypothesized that increased production of CO during RDS might be responsible for increased plasma levels of vasodilatory cGMP and, consequently, low blood pressure observed in infants with RDS. Fifty-two in...

Journal: :Journal of clinical epidemiology 2015
Richard G White Avi J Hakim Matthew J Salganik Michael W Spiller Lisa G Johnston Ligia Kerr Carl Kendall Amy Drake David Wilson Kate Orroth Matthias Egger Wolfgang Hladik

OBJECTIVES Respondent-driven sampling (RDS) is a new data collection methodology used to estimate characteristics of hard-to-reach groups, such as the HIV prevalence in drug users. Many national public health systems and international organizations rely on RDS data. However, RDS reporting quality and available reporting guidelines are inadequate. We carried out a systematic review of RDS studie...

Journal: :Human molecular genetics 2010
Dibyendu Chakraborty Shannon M Conley Michael W Stuck Muna I Naash

Cysteine 150 of retinal degeneration slow protein (RDS) mediates the intermolecular disulfide bonding necessary for large RDS complex assembly and morphogenesis of the rim region of photoreceptor outer segments. Previously, we showed that cones have a different requirement for RDS than rods, but the nature of that difference was unclear. Here, we express oligomerization-incompetent RDS (C150S-R...

2016
Vadivoo Selvaraj Kangusamy Boopathi Ramesh Paranjape Sanjay Mehendale

BACKGROUND AND OBJECTIVES Respondent-driven sampling (RDS) is widely used to sample hidden populations and RDS data are analyzed using specially designed RDS analysis tool (RDSAT). RDSAT estimates parameters such as proportions. Analysis with RDSAT requires separate weight assignment for individual variables even in a single individual; hence, regression analysis is a problem. RDS-analyst is an...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Sharad Goel Matthew J Salganik

Respondent-driven sampling (RDS) is a network-based technique for estimating traits in hard-to-reach populations, for example, the prevalence of HIV among drug injectors. In recent years RDS has been used in more than 120 studies in more than 20 countries and by leading public health organizations, including the Centers for Disease Control and Prevention in the United States. Despite the widesp...

2001
Z. Sazonova

We have proposed the construction of optical quantum computer (OQC) on regular domain structure (RDS) crystal. By using RDS crystal, we can perform all the logical operations on one RDS crystal. Moreover, RDS crystals are parctically independent to the heating effects [4] i.e., can perform logic operations constantly without cooling the RDS crystal [4]. Also, we have proposed the quantum parall...

Journal: :Investigative ophthalmology & visual science 2006
Edwin S Lee Beth Burnside John G Flannery

PURPOSE Peripherin/rds and rom-1 have structural roles in morphogenesis and stabilization of the outer segment, but little is known about their transport and sorting to the rod outer segment. Peripherin/rds and rom-1 trafficking were studied in several knockout and transgenic animal models. METHODS Rod outer segment formation and distribution of peripherin/rds and rom-1 were examined by immun...

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