Synaptotagmin (Syt) constitutes a family of membrane-trafficking proteins, so far nearly 20 Syts have been discovered. Extensive work showed that synatotagmins were a potential Ca2+ sensor for regulated exocytosis. This study was to investigate the expression and location of synaptotagmin II (Syt2) in RBL-2H3 (RBL) and its role in regulating exocytosis of RBL. The expression of Syt2 in RBL was ...

Desain kapal penangkap ikan di Indonesia sangat beragam, salah satu keragamannya terletak pada bentuk linggi haluan kapal. Bentuk yang sesuai dapat meningkatkan performa kinerja Penelitian ini bertujuan untuk mengestimasi kemampuan berdasarkan haluannya terhadap tahanan dan gerak pitching Tiga digunakan dalam penelitian yaitu Raked Bow Tegak (RBT), Landai (RBL), Spoon (SB) dikombinasikan dengan...

Aims: To study RBL-2H3 cell degranulation phenomena induced by some TCMIs through cell morphological and ultra-structural observation, released enzyme activity and establish RBL-2H3 cell degranulation test indicated by βhexosaminidase activity as a method to evaluate TCMIs at nonclinical stage. Methods: RBL-2H3 cells were used to study the degranulation by co-culture with positive control C48/8...

Many new learning models in the 21st century have emerged improving students' academic skills, one of which is research-based (RBL). This pedagogic and constructivist model connects research critical thinking skills (CTS). The results study show that studies empowering CTS using RBL are still limited. Therefore, exploration deeper measurement with were carried out through this study. purpose wa...

BACKGROUND Optimum surgical intervention for low-grade haemorrhoids is unknown. Haemorrhoidal artery ligation (HAL) has been proposed as an efficacious, safe therapy while rubber band ligation (RBL) is a commonly used outpatient treatment. We compared recurrence after HAL versus RBL in patients with grade II-III haemorrhoids. METHODS This multicentre, open-label, parallel group, randomised co...

The protein-tyrosine phosphatase (PTP) Shp2 has been implicated in many immunoreceptor signaling pathways, but its role in immunoreceptor FcεRI signaling, which leads to the activation of mast cells and blood basophils, is still largely undefined. Using Shp2 knockdown RBL-2H3 (RBL) mast cells, we here reported that Shp2 is required for the activation of RBL cells induced by FcεRI. FcεRΙ-evoked ...

We have previously demonstrated immunostimulatory activity of a fungal lectin, Rhizoctonia bataticola lectin (RBL), towards normal human peripheral blood mononuclear cells. The present study aimed to explore the anticancer activities of RBL using human leukemic T-cell lines, Molt-4, Jurkat and HuT-78. RBL exhibited significant binding (>90%) to the cell membrane that was effectively inhibited b...

Opposition-based learning (OBL) scheme is an effective mechanism to enhance soft computing techniques, but it also has some limitations. To extend the OBL scheme, this paper proposes a novel rotation-based learning (RBL) mechanism, in which a rotation number is achieved by applying a specified rotation angle to the original number along a specific circle in two-dimensional space. By assigning d...

BACKGROUND/AIM In this prospective study the results of rubber band ligation (RBL) of symptomatic hemorrhoids in 500 consecutive patients with 2nd (255 cases), 3rd (218 cases) and 4th degree (27 cases) hemorrhoids are presented. METHODS The patients' symptoms were hemorrhage in 142 cases (28.4%), prolapse in 33 cases (6.6%) and both hemorrhage and prolapse in 325 cases (65%). Sixteen patients...

BACKGROUND Imidacloprid has been commonly used as a pesticide for crop protection and acts as nicotinic acetylcholine receptor agonists. Little information about the relationship between imidacloprid and allergy is available. OBJECTIVE This study aims to examine the effects of imidacoprid on IgE-mediated mast cell activation. METHODS The rat basophilic leukemia cell line RBL-2H3 (RBL-2H3 ce...