نتایج جستجو برای: RANK ligand
تعداد نتایج: 178783 فیلتر نتایج به سال:
relationship of salivary rankl and opg with periodontal disease in type 1 diabetic patients dr. ghasemi m .,1 dr. sattari m., 2 dr. khamseh me., 3 dr. kavoli s. 4 1 associate professor, department of periodontics , school of dentistry, islamic azad university. tehran, iran . 2 associate professor, department of immunology , school of medicine, shahid beheshti university of medical sci...
calcification and inflammation are among the important cases of exudative age-related macular degeneration (e-armd). the aim of the present study was to elucidate if there is any relationship between serum osteoprotegerin (opg), soluble receptor activator of nuclear factor-kappa b ligand (rank-ligand) and e-armd. in a cross-sectional study, we compared 45 e-armd patients with 45 matched control...
The interaction of receptor activator of NFκB (RANK), a member of the tumour necrosis factor receptor superfamily, with RANK ligand is crucial for the formation, function and survival of osteoclasts. The role of the cytoplasmic oligomerisation domain (pre-ligand assembly domain; PLAD or 'IVVY' motif) in the ligand-dependent activation of downstream NFκB signalling has not been studied previousl...
Receptor activator of nuclear factor kappa-B ligand (RANKL) is an essential mediator of osteoclast formation, function and survival. In patients with solid tumor metastasis to the bone, targeting the bone microenvironment by inhibition of RANKL using denosumab, a fully human monoclonal antibody (mAb) specific to RANKL, has been demonstrated to prevent tumor-induced osteolysis and subsequent ske...
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