bacteria use a chemical language to communicate with each other which enables them to synchronize gene expression as a result of cell density. this special language which is called quorum sensing (qs) is based on producing and sensing the small signals and eventually leads them to perceive when a minimum population unit is reached. on the contrary, quorum sensing blockade (quorum quenching) has...

Objective(s): Honey’s ability to kill microorganisms and even eradication of chronic infections with drug-resistant pathogens has been documented by numerous studies. The present study is focused on the action of honey in its sub-inhibitory levels to impact on the pathogens coordinated behaviors rather than killing them. Materials and Methods:</strong...

quorum sensing controls the luminescence of vibrio fischeri through the transcriptional activator luxr and the specific autoinducer signal produced by luxi. amino acid sequences of these two genes were analyzed using bioinformatics tools. luxi consists of 193 amino acids and appears to contain five α-helices and six ß-sheets when analyzed by sspro8. luxi belongs to the autoinducer synthetase fa...

background: luxi is a component of the quorum sensing signaling pathway in vibrio fischeri responsible for the inducer synthesis that is essential for bioluminescence. methods: homology modeling of luxi was carried out using phyre2 and refined with the galaxyweb server. five models were generated and evaluated by errat, anolea, qmean6, and procheck. results: five refined models were generated b...

in the present study, variation among different bacterial strains was observed in the plaques of tobacco chewers (tc) as compared to those from normal persons (non tobacco chewers) (ntc). bacterial strain j1 (dominant in the plaques of ntc) did not initiate the process of adhesion (biofilm formation) until it appeared to have reached a required population density necessary for the production of...

introduction: pseudomonas aeruginosa is a gram-negative bacterium that considered as important opportunistic human pathogen. one of the mechanisms that help bacteria to tolerate survival in adverse conditions and resistance to antibiotics is biofilm formation through quorum sensing (qs) signals and toxin-antitoxin (ta) systems. qs and ta are two systems that have important roles in biofilm form...