Quinizarin diester is used as a fluoro-chromogenic substrate of the activity of lipase supported in poly(methylmetacrylate) beads (CALB, Novozym® 435) dispersed in organic solvents. The monoester and diester of quinizarin are both non-fluorescent species contrasting with the enzymatic product quinizarin that shows optical absorption in the visible region and strong fluorescence signal. The enzy...

The anticancer potential of anthraquinones danthron and quinizarin on highly metastatic B16-F10 melanoma murine cells was investigated. Several parameters related to cell proliferation and differentiation, i.e. cell number, intracellular content of polyamines, transglutaminase (EC 2.3.2.13) activity and melanin synthesis were evaluated. Tumor cell growth was strongly reduced after treatment wit...

Quinizarin is a well-suited molecule for obtaining strongly colored materials by atomic layer deposition.

After 35 years the hunt for improved anthracycline antibiotics is unabated but has yet to achieve the levels of clinical success desired. Electrochemical techniques provide a large amount of kinetic and thermodynamic information, but the use of such procedures is hindered by issues of sensitivity and selectivity. This work demonstrates how by harnessing the mechanism of catalytic reduction of o...

The investigation of sweating represents a special and relatively new approach to clinical and physiological research on cutaneous fupction.The recent war has afforded great opportunities for investigating the phenomena resulting from injuries of the nervous system affecting the sweat mechanisms, and the Quinizarin method (L. Guttmann, 1937, '38, '40, '4I, '46; Highet, I942; Lewin, 1943; Seddon...

The development of an optical pH sensor based on immobilization of quinizarin (1,4-dihydroxyanthraquinone) on a triacetylcellulose membrane was described. The resulting membrane exhibited fast color change from yellow to violet, while changing the pH in alkaline region. The immobilized quinizarin showed a broader dynamic range from (pH 9.4-11.4) with respect to free form (pH 8.8-10.4). The sens...

We report photoacid-induced nonerasable recording in tert-butoxycarbonyl-protected quinizarin methacrylate polymers for three-dimensional optical memory. 1m/s-speed recording was achieved using an 800 nm femtosecond laser at an 80MHzrepetition rate, without a postexposure bake after laser irradiation. Three-layer recording indicates that no optical damage during recording enables modulation of ...

An unprecedented class of macrocycles with intrinsic fluorescence consisting of phenolic trimers and quinizarin is developed. Though they are lacking strong hydrogen bonds as observed in calixarenes, the two examples introduced here each adopt a vase-like conformation with all four aromatic units pointing in one direction (syn orientation). This "cone" conformation has been confirmed by NMR spe...