myostatin or growth and differentiation factor 8 (gdf8), has been known as the factor causing double muscling phenotypes in which a series of mutations make the myostatin protein inactive, hence disabling it to regulate the deposition of muscle fibre. this phenotype happens with high frequency in a breed of sheep known as the texel. quantitative trait loci (qtl) studies show that a portion of t...

Sporulation efficiency in the yeast Saccharomyces cerevisiae is a well-established model for studying quantitative traits. A variety of genes and nucleotides causing different sporulation efficiencies in laboratory, as well as in wild strains, has already been extensively characterised (mainly by reciprocal hemizygosity analysis and nucleotide exchange methods). We applied a different strategy ...

an f2 japanese quail population was developed by crossing two strains (wild and white) to map quantitative trait loci (qtl) for performance and carcass traits. a total of 472 f2 birds were reared and slaughtered at 42 days of age. performance and carcass traits were measured on all of the f2 individuals. parental (p0), f1 and f2 individuals were genotyped with 3 microsatellites from quail chrom...

Quantitative trait loci (QTL) with small effects on phenotypic variation can be difficult to detect and analyze. Because of this a large fraction of the genetic architecture of many complex traits is not well understood. Here we use sporulation efficiency in Saccharomyces cerevisiae as a model complex trait to identify and study small-effect QTL. In crosses where the large-effect quantitative t...

The rapid increase in high-throughput single-nucleotide polymorphism data has led to a great interest in applying genome-wide evaluation methods to identify an individual's genetic merit. Genome-wide evaluation combines statistical methods with genomic data to predict genetic values for complex traits. Considerable uncertainty currently exists in determining which genome-wide evaluation method ...

Myostatin or growth and differentiation factor 8 (GDF8), has been known as the factor causing double muscling phenotypes in which a series of mutations make the myostatin protein inactive, hence disabling it to regulate the deposition of muscle fibre. This phenotype happens with high frequency in a breed of sheep known as the Texel. Quantitative trait loci (QTL) studies show that a portion of t...