Intact pyridoxine glucoside showed about 20% of microbiological activity of equivalent mole of pyridoxine for Saccharomyces carlsbergensis 4228 ATCC 9080. The activity was gradually increased accompanied with the prolonged incubation. It seems that pyridoxine glucoside is hydrolyzed to pyridoxine and glucose by a-glucosidase of Saccharomyces carlsbergensis 4228 ATCC 9080 and can be bioassayed a...

OBJECTIVE To evaluate the behavioral effect of pyridoxine on the antidepressant action of imipramine. METHODS Male Wistar albino mice of weights 25-35gms were used. Two experiments were carried out; the first on the acute effect of pyridoxine on the duration of immobility, and the second on the sub-chronic effects of pyridoxine alone and in combination with imipramine. In the first experiment...

Pyridoxal phosphate is the coenzyme of various decarboxylases involved in the formation of monoamine neurotransmitters such as gamma-aminobutyric acid, serotonin, dopamine, and norepinephrine. Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls. Hypothalamic contents of pyridoxal phosphat...

Coelogyne is a native Indonesian orchid with relatively large flower sizes and attractive colors. The purpose of this study was to determine the effect giving concentrations Potassium Dihydrogen Phosphate (KH2PO4) Pyridoxine in Murashige And Skoog media on growth Rochussenii De Vriese subculture. research conducted at UPT Tissue Culture Laboratory Seeds Food Crops, Horticulture, Plantation, Ria...

Pyridoxine-deficient young rats (3 weeks old) had significantly reduced levels of pituitary TSH, serum thyroxine (T4) and tri-iodothyronine (T3) compared with pyridoxine-supplemented rats. The status of the pituitary-thyroid axis of normal, pyridoxine-supplemented and pyridoxine-deficient rats was evaluated by studying the binding parameters of [3H](3-methyl-histidine2)TRH in the pituitary of t...

Intractable epilepsy is a common clinical problem in pediatrics and approximately 13% of children with epilepsy experience intractable seizures. To determine the efficacy of pyridoxine in treating seizures, 30 infants and children with recurrent seizures were enrolled in the present study. All of them were treated with high-dose oral pyridoxine (40 mg/kg/day), as an adjunct to antiepileptic...

Attempts have been made to clarify the effect of pyridoxine deficiency as well as its overdosis on growth of transplantable tumors in mouse and rat. The growth of transplantable solid tumor in pyridoxine deficient animals was remarkably suppressed while that of ascites tumor was not. The tumor bearing host was administered with a large amounts of pyridoxine and pyridoxal phosphate resulting in ...

Borax is one of the compounds boron (B), which widely used as an anti-fungal, wood preservative, and antiseptic in cosmetics. Boron can form complexes with biomolecules such pyridoxine, so it interesting to know interaction between borax pyridoxine. This study seeks investigate complexation boron, obtained from borax, pyridoxine under various conditions time, temperature, amount The resulting c...

MICROCYTIC hypochromic anemia induced by a diet deficient in pyridoxine is well documented in swine,’ monkeys,2 dogs,3 cats,4 ducks,5 and chicks.#{176}In man, pyridoxine deficiency anemia was first described in 1956 by Harris et al.;7 subsequently an increasing number of cases have been reported by others. In 1953, Synderman et al.8 produced pyridoxine deficiency in two infants with cerebral de...

The natural vitamin, pyridoxine, in the millimolar range is toxic to cultured rat hepatoma cells. A pyridoxine-resistant Fu5-5 rat hepatoma cell line was established by a stepwise increase in the concentration of pyridoxine in the medium. The newly established cell line, referred to as clone 10 (Cl.10), is resistant to killing by pyridoxine in concentrations up to 5 mM. Saturation kinetics for ...