The Psoralea corylifolia is commonly known as babchi or bakuchi, used to cure psoriasis, leprosy, leucoderma, diabetes, indigestion, constipation, cardiac failure, coughs, asthma and osteoporosis. The present study was aimed to investigate the Physico-chemical and preliminary phytochemical screening of Psoralea corylifolia seeds. The extracts of Psoralea corylifolia seeds were prepared using di...

Ethanolic extracts of 20 plant species, selected from the ethnobotanical literature, were analysed for their pharmacological potential as antineoplastic agents against the HEp-2 cell line. Psoralea corylifolia and E. grandidens were the most efficacious species eliciting IC50 values of 22 microg/ml and 57 microg/ml respectively. Psoralea corylifolia, additionally tested against lung carcinoma (...

A simple, accurate ,precise, sensitive spectrofluorometric method was developed for estimation of psoralen in methanolic extract of Psoralea corylifolia seeds. It showed strong intense blue fluorescence having excitation and emission wavelength 290nm and 427.66 nm, respectively. Linear relationship for the fluorescence intensity was obtained in the range 50-100 μg /mL. Limit of detection and li...

Over 80 taxa of mostly agriculturally important legumes were surveyed as sources of the metabolites, genistein and daidzein. Remarkably high concentrations (over 2 g.kg-1 dry weight) of the anticancer metabolite, genistein, were found in the leaves of Psoralea corylifolia (Indian bread root). All other legumes, with the exception of fermented soybean miso, had genistein levels < 400 mg.kg-1 dry...

Evaluation of effect of the aqueous, alcohol and chloroform extract of Psoralea corylifolia on sexual behaviour of male albino rats. Plant extracts (aqueous, alcohol and chloroform) at doses of 100, 200 and 400 mg/kg were administrated for 21 days. The female rats involved in mating were made receptive by hormonal treatment. The general mating behaviour, libido and potency along with orientatio...

BACKGROUND Mitochondrial dysfunction has been implicated in neuronal apoptosis associated with neurodegenerative diseases such as Huntington's disease (HD). Animals that are administered 3-nitropropionic acid (3-NP), a mitochondrial toxin that specifically inhibits complex II of the mitochondrial electron transport chain, manifest HD-like symptoms. METHODS Psoralea corylifolia Linn seed extra...

Psoralea corylifolia L. (Fabaceae) is a widely used medical plant in China. This study was designed to screen and identify bioactive compounds with anticancer activity from the seeds of Psoralea corylifolia L. One volatile fraction (fraction I) and three other fractions (fraction II, III, IV) from methanol extraction of P. corylifolia L. were obtained. Bioactivities of these fractions were eval...

Flavonoids and coumarins are the major bioactive constituents identified in Psoralea corylifolia. The active fraction isolated from fruits, seeds and roots possesses antibacterial, antioxidative and immunomodulatory properties. Neobavaisoflavone is one of the flavonoids found in Psoralea corylifolia. In the present study we investigated in vitro the anti-inflammatory activity of neobavaisoflavo...

High-valued medicinal plants Achillea millefolium, Acorus calamus, Arnebia nobilis, Fumaria indica, Gymnema sylvestre, Origanum vulgare, Paeonia emodi, Peganum harmala, Psoralea corylifolia, Rauwolfia serpentina, and Vetiveria zizanioides were identified with the help of taxonomical markers and investigated for characterization and palynological studies. These parameters are used to analyze the...