Background: Pseudoexfoliation syndrome is one of the most common identifiable causes of open angle glaucoma. It has unknown etiology and pathogenesis. Infection, possibly viral, is one of the proposed pathogenic mechanisms in this condition. In the present study the presence of herpes simplex virus (HSV) in specimens of anterior lens capsule of patients with pseudoexfoliation syndrome has been ...

Pseudoexfoliation syndrome is an agerelated disease characterized by the pathological production and accumulation of an abnormal extracellular fibrillar material over ocular tissues as well as other tissues and organs in the body such as the lung, liver, kidney, gall bladder, and cerebral meninges. The specific pathogenesis of pseudoexfoliation syndrome and the exact chemical composition of the...

PURPOSE Pseudoexfoliation syndrome is a major risk factor for the development of glaucoma. Following recent reports of a strong association of coding variants in the lysyl oxidase-like 1 (LOXL1) gene with this syndrome but low penetrance and variable disease frequency between different populations, we aimed to identify additional genetic factors contributing to the disease. The clusterin (CLU) ...

purpose: to report a case of pseudoexfoliation syndrome in young keratoconus patient following penetrating keratoplasty. case report: a 37 year old man who underwent penetrating keratoplasty 13 years ago in his left eye due to keratoconus developed pseudoexfoliation (pex) syndrome in the operated eye. apart from pex material deposition on the crystalline lens ophthalmic exam was within normal l...

The purpose of this study was to assess the prevalence of pseudoexfoliation syndrome and pseudoexfoliation glaucoma and to evaluate its association with open-angle glaucoma in patients attending the Department of Ophthalmology, Dr Tomislav Bardek General Hospital in Koprivnica, northwestern Croatia. This prospective study was conducted at Dr Tomislav Bardek General Hospital between December 201...

PURPOSE To determine the relationship between cerebro vascular disease and pseudoexfoliation syndrome. MATERIALS AND METHODS This cross-sectional case control study consisted of 50 patients with ischemic-type cerebro vascular disease and 50 control subjects. All subjects were investigated for diabetes mellitus and hypertension status and underwent a detailed ophthalmic examination. A diagnosi...

Pseudoexfoliation syndrome (PES) is a systemic disorder caused by progressive accumulation of extracellular material over various tissues. PES usually determines increased intraocular pressure, changes in the anatomical aspects of the optic nerve, and visual field alterations leading to the diagnosis of pseudoexfoliation glaucoma (PEG). Use of topical medical treatment usually leads to poor res...

Pseudoexfoliation syndrome is a common clinically important systemic condition characterized by the pathological production and accumulation of an abnormal fibrillar extracellular material in many intraocular and extraocular tissues. Many studies have shown that pseudoexfoliation syndrome patients with higher rates of intraoperative complications during cataract surgery compared to the patients...