normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background: in radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness. metho...

Introduction: The proton beam produced in particle accelerators has an appropriate therapeutic potential. In this research, proton therapy of breast cancer is simulated using the MCNPX code in a MIRD phantom, also the contribution of scattered neutron dose during the proton therapy were calculated for the Heart, Lung and Liver.   Materials and Methods: For si...

Background: The present study aimed to investigate the equivalent dose in vital organs, including heart and lung, due to secondary particles produced during breast proton therapy. Materials and Methods: The numerical ORNL female-phantom was improved and simulated using the Monte Carlo MCNPX code. The depth-dose profile of proton beams with different energies was simulated. The proper energy ran...

Background: In radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. Heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness.Methods: In this study, we used Monte Carlo method-based Geant4 toolkit to s...

Introduction: Many study shown the effectiveness dose enhancement with gold nanoparticles (GNPs), especially with low-energy x-rays. Recently, proton beam radiation therapy (PBRT) has attention as a treatment for tumors. The advantage in PBRT, which releases high dose at the controllable Bragg peak position that localized for Au target and the released dose increased in depth....

Introduction: Proton radiotherapy is the one of advanced teletherapy methods. The protons deposit their maximum energy in a position called Bragg peak. Therefore, for treatment of cancer, the tumor should be placed at the Bragg peak or SOBP. The scattered photons and neutrons is a challenge in proton radiotherapy. The aim of this study is calculation of absorbed dose from scatt...

Introduction: Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed. Three alpha particles with an average energy around 4MeV are emitted from the point of reaction between a proton and boron. In addition, the 719 keV prompt gamma emitted by the proton Boron fusion reactions can be used for on-...

Purpose: The recommended value for the relative biological effectiveness (RBE) of proton beams is currently assumed to be 1.1. However, there is increasing evidence that RBE increases towards the end of proton beam range that may increase the biological effect of proton beam in the distal regions of the dose deposition. Methods: A computational approach is presented for estimating the biologica...