Nitrogen fertilizer application rates in intensive agricultural systems have increased dramatically in recent years, especially in protected vegetable production systems. This excessive use of nitrogen fertilizer has resulted in soil secondary salinity, which has become a significant environmental stress for crops such as cucumber, in the protected farmlands. It is thus necessary to illuminate ...

The present study was conducted to study the effect of protected-glutamine (Gln) supplementation on dry matter intake (DMI), milk yield (MY) and composition, somatic cell counts (SCC) and blood parameters in fresh cows. Forty Holstein cows at zero day of parturition (calving day = day 0) were divided into four groups (n=10), and fed (ad libitum) with one of the diets including: basal d...

Glutamine is an important mitochondrial substrate implicated in the protection of cells from oxidant injury, but the mechanisms of its action are incompletely understood. Human pulmonary epithelial-like (A549) cells were exposed to 95% O2 for 4 days in the absence and presence of glutamine. Cell proliferation in normoxia was dependent on glutamine, and glutamine deprivation markedly accelerated...

The reaction of phenylglyoxal with two enzymes in which ATP plays a complex role has been studied. Both ovine brain glutamine synthetase and Escherichia coli carbamyl phosphate synthetase [carbamoyl-phosphate synthase (glutamine); ATP:carbamate phosphotransferase (dephosphorylating, amido-transferring); EC 2.7.2.9]were inactivated by phenylglyoxal. The specificity of this reagent for arginyl re...

Poly glutamine and glutamine-rich peptides play a central role in plethora of pathological aggregation events. However, biophysical characterization soluble oligomers -the most toxic species involved these processes- remains elusive due to their structural heterogeneity dynamical nature. Here, we exploit the high spatio-temporal resolution coarse-grained simulations as computational microscope ...

Intestinal ischemia-reperfusion (IIR) injury affects other organs, like the liver. Glutamine may offer liver protection, following IIR injury. Four groups of rats were studied. In Group A, the animals were subjected to 90 minutes of IIR. In Group B Alanyl-Glutamine dipeptide was administered prior to IIR. Group C, was the sham, and in Group D, the animals were given Alanyl-Glutamine dipeptide, ...

Background. Maximal Aerobic Power is related to many quantities and qualities such as supplements. Objectives. The purpose of the present study was to describe the effect of short-term supplementation of glutamine and glucose on hemoglobin and maximum aerobic power in female athletes. Methods. In this quasi-experimental study, 40 female athletes (age 21.9±2.6 years, height 161.8&...

Carbamoyl phosphate synthetase (CPS) from Escherichia coli catalyzes the formation of carbamoyl phosphate from 2 mol of ATP, bicarbonate, and glutamine. CPS was inactivated by the glutamine analog, acivicin. In the presence of ATP and bicarbonate the second-order rate constant for the inactivation of the glutamine-dependent activities was 4.0 x 10(4) m(-1) s(-1). In the absence of ATP and bicar...

The objectives of this study was to investigate whether consuming of protected glutamine (PG) before parturition in close up period would affect dry matter intake (DMIkg/d), blood urea nitrogen (BUNmg/dl), body condition score (BCS) and biomarkers of oxidative stress, glutathione peroxidase activity (GPX units/ml PCV) and Total Antioxidant Status (TASmmol/L). Thirty six pregnant Holstein dairy ...

Background: A low level of L-glutamine, a precursor of nicotinamide adenine dinucleotide (NAD) in red blood cells (RBCs), is identified as an underlying mechanism for the potential decrement of the NAD redox and the incidence of pain crisis in sickle cell anemia (SCA). The aim of this study is to assess the impact of oral L-glutamine therapy on pain crisis reduction in patients with SCA and sic...