نتایج جستجو برای: Prosite

تعداد نتایج: 274  

Journal: :Nucleic Acids Research 2006

Journal: :Applied bioinformatics 2002
Alexandre Gattiker Elisabeth Gasteiger Amos Bairoch

Many different software tools are available publicly to scan the PROSITE database of protein families. However, none of them, to our knowledge, wholly implements the PROSITE syntax, or satisfies all the rules for scanning a pattern against a sequence. We hereby propose a strict definition of how a PROSITE pattern is to be scanned against a sequence, and provide a reference implementation of a t...

Journal: :Briefings in bioinformatics 2002
Christian J. A. Sigrist Lorenzo Cerutti Nicolas Hulo Alexandre Gattiker Laurent Falquet Marco Pagni Amos Bairoch Philipp Bucher

Among the various databases dedicated to the identification of protein families and domains, PROSITE is the first one created and has continuously evolved since. PROSITE currently consists of a large collection of biologically meaningful motifs that are described as patterns or profiles, and linked to documentation briefly describing the protein family or domain they are designed to detect. The...

2008
Nicolas Hulo Amos Bairoch Virginie Bulliard Lorenzo Cerutti Béatrice A. Cuche Edouard De Castro Corinne Lachaize Petra S. Langendijk-Genevaux Christian J. A. Sigrist

PROSITE consists of documentation entries describing protein domains, families and functional sites, as well as associated patterns and profiles to identify them. It is complemented by ProRule, a collection of rules based on profiles and patterns, which increases the discriminatory power of profiles and patterns by providing additional information about functionally and/or structurally critical...

Bahram Goliaei Mehdi Sadeghi Mohammad-Hadi Foroughmand-Araabi

PROSITE database contains a set of entries corresponding to protein families, which are used to identify the family of a protein from its sequence. Although patterns and profiles are developed to be very selective, each may have false positive or negative hits. Considering false positives as items that reduce the selectiveness of a pattern, then, the more selective pattern we have, a more accur...

Journal: :Nucleic Acids Research 2007

2010
Christian J. A. Sigrist Lorenzo Cerutti Edouard De Castro Petra S. Langendijk-Genevaux Virginie Bulliard Amos Bairoch Nicolas Hulo

PROSITE consists of documentation entries describing protein domains, families and functional sites, as well as associated patterns and profiles to identify them. It is complemented by ProRule, a collection of rules based on profiles and patterns, which increases the discriminatory power of these profiles and patterns by providing additional information about functionally and/or structurally cr...

Journal: :Nucleic acids research 2004
Nicolas Hulo Christian J. A. Sigrist Virginie Le Saux Petra S. Langendijk-Genevaux Lorenza Bordoli Alexandre Gattiker Edouard De Castro Philipp Bucher Amos Bairoch

The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE web page has been redesigned and several tools have been implemented to help the user d...

Journal: :Nucleic Acids Research 2006
Nicolas Hulo Amos Bairoch Virginie Bulliard Lorenzo Cerutti Edouard De Castro Petra S. Langendijk-Genevaux Marco Pagni Christian J. A. Sigrist

The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to a documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE database is now complemented by a series of rules that can give more precise informat...

2013
Thierry Schüpbach Marco Pagni Alan Bridge Lydie Bougueleret Ioannis Xenarios Lorenzo Cerutti

SUMMARY The PROSITE resource provides a rich and well annotated source of signatures in the form of generalized profiles that allow protein domain detection and functional annotation. One of the major limiting factors in the application of PROSITE in genome and metagenome annotation pipelines is the time required to search protein sequence databases for putative matches. We describe an improved...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید