bordetella pertussis infects the respiratory tract of the human host and causes whooping cough in children. the nature of immunity against bordetella pertussis infection and disease is poorly understood. the aim of this study was to investigate cell mediated immunity in mice immunized with outer membrane component of cell wall, of b. pertussis. a group of mice were immunized with outer membrane...

introduction: the native inability of nervous system to regenerate, encourage researchers to consider neural tissue engineering as a potential treatment for spinal cord injuries. considering the suitable characteristics of induced pluripotent stem cells (ipscs) for tissue regeneration applications, in this study we investigated the adhesion, viability and proliferation of neural progenitors (de...

aim : in this paper effect of combinational usage of calprotectin and etoposide on ags cell line is studied. background : application of combined toxic agents such as etoposide and cicplatin are commonly used for chemotherapy purposes. as a matter of fact, calprotectin and etoposide were both applied on human gastric adenocarcinoma cell line (ags) as antitumor agents. both calprotectin and etop...

the ethyl acetate partition of dried methanolic extract of aerial parts of euphorbia microsciadia (euphorbiaceae) afforded three pentacyclic triterpenes, betulinic acid (1) from lupane type, oleanolic acid (2) from oleane type and ursolic acid (3) from ursane type triterpenes that are reported for the first time in this plant. these three compounds were structurally compared through their mass ...

the cytotoxic chloroform fraction of euphorbia aellenii afforded two cycloartane type triterpenes — cycloart-25-en-3,24-diol (1) and 24-methylene-cycloartan-3-ol (2) — for the first time from this plant. preparation of cycloartane derivatives, 3, 24-o-diacetyl-cycloart-25-en as compound 3 and 3-o-acetyl-24-methylene-cycloartan (4) were conducted by acetylating of 1 and 2, respectively. the ...

Background: Colorectal cancer (CRC) is one of the most common causes of cancer-related death in the world. The expression of N-myc downstream-regulated gene 2 (NDRG2) is down-regulated in CRC. The aim of this study was to investigate the effect of NDRG2 overexpression on cell proliferation and invasive potential of SW48 cells.Methods: SW48 cells were transfected with a plasmid overexpressing ND...

Objective(s): To explore the correlation between expression patterns and functions of miR-383 and LDHA in hepatocellular cancer (HCC). Materials and Methods: We detected the expression of miR-383 and LDHA in 30 HCC tissues and their matched adjacent normal tissues using qRT-PCR. Then we performed MTT assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...

objective(s): to explore the correlation between expression patterns and functions of mir-383 and ldha in hepatocellular cancer (hcc). materials and methods: we detected the expression of mir-383 and ldha in 30 hcc tissues and their matched adjacent normal tissues using qrt-pcr. then we performed mtt assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...