results a significant higher serum pab value was observed in shift working and daytime nurses (152.28 ± 43.64 hk) in comparison to the control group (63.64 ± 34.41 hk index), p value = 0.001. in day time nurses, also serum pab between male (119.09 ± 47.14 hk) and female (162.53 ± 37.02 hk) in nursing workers was significant, p value = 0.005. in the night shift working nurses, there was also a s...

background : gliomas are the most common primary brain tumors of the central nervous system. among a number of different bio-molecular events, molecular connections between oxidative stress pathways and their development is prevalent. oxidative stress is the consequence of an imbalance between pro-oxidant factors and antioxidant defense. this imbalance may lead to dna damage and changes in grow...

objective: crocin, the carotenoid isolated from saffron, has numerous medicinal properties which include anticancer and antioxidant activities. some antioxidants, such as carotenoids, can act as pro-oxidants at higher dosages and therefore induce tissue damage. in this situation antioxidant defense systems in the liver activate to prevent tissue damage. this study investigates the possible toxi...

introduction: the molecular mechanisms involved in pathogenesis of esophageal cancer have been the main concern of several studies. in this study, we aimed to investigate the changes of serum prooxidant-antioxidant balance (pab) value as a redox index, as well as serum c-reactive protein (crp) compared to healthy control group. materials and methods: in a cross-sectional study, blood samples we...

Immune system functioning and maintenance entails costs which may limit investment into other processes such as reproduction. Yet, the proximate mechanisms and 'currencies' mediating the costs of immune responses remain elusive. In vertebrates, up-regulation of the innate immune system is associated with rapid phagocytic production of pro-oxidant molecules (so-called 'oxidative burst' responses...

Excess of reactive oxygen can lead to membrane damage, accumulation lipid, protein, and nucleic acid oxidation products, deficiency reduced pyridine nucleotides phospholipids mitochondrial membranes, then electrolyte imbalance, swelling, uncoupling phosphorylation processes, ischemic neuronal death. Thus, the study oxidative stress antioxidant system activity is relevant.
 The aim examine ...

background & aim: the most common primary brain tumors of the central nervous system are gliomas. among a number of different biomolecular events, a strong relation between oxidative stress pathways and the development of this cancer has been proved. oxidative stress (os) is the consequence of an imbalance between pro-oxidants and antioxidants towards pro-oxidants. the pro-oxidants cause lipid ...

Background & Aim: The most common primary brain tumors of the central nervous system are gliomas. Among a number of different biomolecular events, a strong relation between oxidative stress pathways and the development of this cancer has been proved. Oxidative stress (OS) is the consequence of an imbalance between pro-oxidants and antioxidants towards pro-oxidants. The pro-oxidants cause lipid ...

INTRODUCTION Intra-abdominal hypertension (IAH) is known as a common, serious complication in critically ill patients. Bacterial translocation and permeability changes are considered the pathophysiological bases for IAH-induced enterogenic endotoxemia and subsequent multiorgan failure. Nevertheless, the effects of slightly elevated intra-abdominal pressures (IAPs) on the intestinal mucosa and t...