Primary cardiac osteosarcoma is a very rare malignancy with a high incidence of local recurrence and systemic metastasis, contributing to the poor prognosis. Radiological modalities are commonly used for the evaluation of cardiac masses. 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) positron emission tomography/computed tomography is a valuable whole-body imaging modality in ...

Little is reported about primary cardiac osteosarcoma from mitral valve. We report a surgical case of primary cardiac osteosarcoma arising from mitral valve. The patient was a 54-year-old woman with congestive heart failure caused by mitral regurgitation due to a tumor (30 × 20 mm) from the posterior leaflet. We performed complete resection of the tumor combined with the mitral valve and replac...

•This is the first reported case describing a female with primary uterine osteosarcoma that exhibited cardiac and pulmonary metastases.•Although extremely rare, uterine osteosarcomas, like leiomyosarcomas, do respond to doxorubicin and ifosfamide.•Uterine osteosarcoma behaves aggressively and is associated with a poor prognosis.

Primary cardiac tumors are uncommon and cardiac osteosarcoma is a rare disease. While complete surgical resection is considered to be the best treatment option for cardiac osteosarcomas, local and metastatic recurrences present challenges and indicate a poor prognosis. A combination of surgical resection with radio- and/or chemotherapy is a more effective course of treatment for osteosarcoma. I...

background: understanding the differences in genetics of malignancies is crucial for therapeutic decisions. this systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. material and methods: we performed a systematic review of the literature published on genetics of pediatrics bone tumors, using pubmed, google scholar, scie...

We describe here a 42-year-old woman who was admitted to hospital with a pedunculated mass in her left atrium. She was diagnosed with a primary cardiac osteosarcoma with special immunohistochemical characteristics. Echocardiography and computed tomography can be used to differentiate cardiac osteosarcomas from routine intracardiac tumors. The patient was treated by surgical removal of the mass....

Osteosarcoma (osteogenic sarcoma: OS) is the most common primary malignant bone tumor of long bones, whereas primary osteosarcoma of chest wall, especially in sternum, is extremely rare. We report a 57-year-old man with an immobile slow growing mass located in the middle of the sternum. The patient had no significant pain or tenderness and the past medical history was not remarkable. CT-scan sh...